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261 results

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NLRP3 inflammasomes are required for atherogenesis and activated by cholesterol crystals.
Duewell P, Kono H, Rayner KJ, Sirois CM, Vladimer G, Bauernfeind FG, Abela GS, Franchi L, Nuñez G, Schnurr M, Espevik T, Lien E, Fitzgerald KA, Rock KL, Moore KJ, Wright SD, Hornung V, Latz E. Duewell P, et al. Among authors: wright sd. Nature. 2010 Apr 29;464(7293):1357-61. doi: 10.1038/nature08938. Nature. 2010. PMID: 20428172 Free PMC article.
High-density lipoprotein mediates anti-inflammatory reprogramming of macrophages via the transcriptional regulator ATF3.
De Nardo D, Labzin LI, Kono H, Seki R, Schmidt SV, Beyer M, Xu D, Zimmer S, Lahrmann C, Schildberg FA, Vogelhuber J, Kraut M, Ulas T, Kerksiek A, Krebs W, Bode N, Grebe A, Fitzgerald ML, Hernandez NJ, Williams BR, Knolle P, Kneilling M, Röcken M, Lütjohann D, Wright SD, Schultze JL, Latz E. De Nardo D, et al. Among authors: wright sd. Nat Immunol. 2014 Feb;15(2):152-60. doi: 10.1038/ni.2784. Epub 2013 Dec 8. Nat Immunol. 2014. PMID: 24317040 Free PMC article.
Cyclodextrin promotes atherosclerosis regression via macrophage reprogramming.
Zimmer S, Grebe A, Bakke SS, Bode N, Halvorsen B, Ulas T, Skjelland M, De Nardo D, Labzin LI, Kerksiek A, Hempel C, Heneka MT, Hawxhurst V, Fitzgerald ML, Trebicka J, Björkhem I, Gustafsson JÅ, Westerterp M, Tall AR, Wright SD, Espevik T, Schultze JL, Nickenig G, Lütjohann D, Latz E. Zimmer S, et al. Among authors: wright sd. Sci Transl Med. 2016 Apr 6;8(333):333ra50. doi: 10.1126/scitranslmed.aad6100. Sci Transl Med. 2016. PMID: 27053774 Free PMC article.
Infusion of Reconstituted High-Density Lipoprotein, CSL112, in Patients With Atherosclerosis: Safety and Pharmacokinetic Results From a Phase 2a Randomized Clinical Trial.
Tricoci P, D'Andrea DM, Gurbel PA, Yao Z, Cuchel M, Winston B, Schott R, Weiss R, Blazing MA, Cannon L, Bailey A, Angiolillo DJ, Gille A, Shear CL, Wright SD, Alexander JH. Tricoci P, et al. Among authors: wright sd. J Am Heart Assoc. 2015 Aug 25;4(8):e002171. doi: 10.1161/JAHA.115.002171. J Am Heart Assoc. 2015. PMID: 26307570 Free PMC article. Clinical Trial.
Reconstituted high-density lipoprotein can elevate plasma alanine aminotransferase by transient depletion of hepatic cholesterol: role of the phospholipid component.
Herzog E, Pragst I, Waelchli M, Gille A, Schenk S, Mueller-Cohrs J, Diditchenko S, Zanoni P, Cuchel M, Seubert A, Rader DJ, Wright SD. Herzog E, et al. Among authors: wright sd. J Appl Toxicol. 2016 Aug;36(8):1038-47. doi: 10.1002/jat.3264. Epub 2015 Dec 9. J Appl Toxicol. 2016. PMID: 26651060
Enhanced HDL Functionality in Small HDL Species Produced Upon Remodeling of HDL by Reconstituted HDL, CSL112: Effects on Cholesterol Efflux, Anti-Inflammatory and Antioxidative Activity.
Didichenko SA, Navdaev AV, Cukier AM, Gille A, Schuetz P, Spycher MO, Thérond P, Chapman MJ, Kontush A, Wright SD. Didichenko SA, et al. Among authors: wright sd. Circ Res. 2016 Sep 2;119(6):751-63. doi: 10.1161/CIRCRESAHA.116.308685. Epub 2016 Jul 19. Circ Res. 2016. PMID: 27436846 Free PMC article. Clinical Trial.
A Consensus Definitive Classification of Scavenger Receptors and Their Roles in Health and Disease.
PrabhuDas MR, Baldwin CL, Bollyky PL, Bowdish DME, Drickamer K, Febbraio M, Herz J, Kobzik L, Krieger M, Loike J, McVicker B, Means TK, Moestrup SK, Post SR, Sawamura T, Silverstein S, Speth RC, Telfer JC, Thiele GM, Wang XY, Wright SD, El Khoury J. PrabhuDas MR, et al. Among authors: wright sd. J Immunol. 2017 May 15;198(10):3775-3789. doi: 10.4049/jimmunol.1700373. J Immunol. 2017. PMID: 28483986 Free PMC article.
261 results