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The OPA1-dependent mitochondrial cristae remodeling pathway controls atrophic, apoptotic, and ischemic tissue damage.
Varanita T, Soriano ME, Romanello V, Zaglia T, Quintana-Cabrera R, Semenzato M, Menabò R, Costa V, Civiletto G, Pesce P, Viscomi C, Zeviani M, Di Lisa F, Mongillo M, Sandri M, Scorrano L. Varanita T, et al. Among authors: sandri m. Cell Metab. 2015 Jun 2;21(6):834-44. doi: 10.1016/j.cmet.2015.05.007. Cell Metab. 2015. PMID: 26039448 Free PMC article.
FoxO3 controls autophagy in skeletal muscle in vivo.
Mammucari C, Milan G, Romanello V, Masiero E, Rudolf R, Del Piccolo P, Burden SJ, Di Lisi R, Sandri C, Zhao J, Goldberg AL, Schiaffino S, Sandri M. Mammucari C, et al. Among authors: sandri c, sandri m. Cell Metab. 2007 Dec;6(6):458-71. doi: 10.1016/j.cmet.2007.11.001. Cell Metab. 2007. PMID: 18054315 Free article.
Skeletal muscle is a primary target of SOD1G93A-mediated toxicity.
Dobrowolny G, Aucello M, Rizzuto E, Beccafico S, Mammucari C, Boncompagni S, Belia S, Wannenes F, Nicoletti C, Del Prete Z, Rosenthal N, Molinaro M, Protasi F, Fanò G, Sandri M, Musarò A. Dobrowolny G, et al. Among authors: sandri m. Cell Metab. 2008 Nov;8(5):425-36. doi: 10.1016/j.cmet.2008.09.002. Cell Metab. 2008. PMID: 19046573 Free article.
Autophagy is required to maintain muscle mass.
Masiero E, Agatea L, Mammucari C, Blaauw B, Loro E, Komatsu M, Metzger D, Reggiani C, Schiaffino S, Sandri M. Masiero E, et al. Among authors: sandri m. Cell Metab. 2009 Dec;10(6):507-15. doi: 10.1016/j.cmet.2009.10.008. Cell Metab. 2009. PMID: 19945408 Free article.
Mitochondrial fission and remodelling contributes to muscle atrophy.
Romanello V, Guadagnin E, Gomes L, Roder I, Sandri C, Petersen Y, Milan G, Masiero E, Del Piccolo P, Foretz M, Scorrano L, Rudolf R, Sandri M. Romanello V, et al. Among authors: sandri c, sandri m. EMBO J. 2010 May 19;29(10):1774-85. doi: 10.1038/emboj.2010.60. Epub 2010 Apr 16. EMBO J. 2010. PMID: 20400940 Free PMC article.
Lifelong physical exercise delays age-associated skeletal muscle decline.
Zampieri S, Pietrangelo L, Loefler S, Fruhmann H, Vogelauer M, Burggraf S, Pond A, Grim-Stieger M, Cvecka J, Sedliak M, Tirpáková V, Mayr W, Sarabon N, Rossini K, Barberi L, De Rossi M, Romanello V, Boncompagni S, Musarò A, Sandri M, Protasi F, Carraro U, Kern H. Zampieri S, et al. Among authors: sandri m. J Gerontol A Biol Sci Med Sci. 2015 Feb;70(2):163-73. doi: 10.1093/gerona/glu006. Epub 2014 Feb 18. J Gerontol A Biol Sci Med Sci. 2015. PMID: 24550352 Clinical Trial.
Atrogin-1 deficiency promotes cardiomyopathy and premature death via impaired autophagy.
Zaglia T, Milan G, Ruhs A, Franzoso M, Bertaggia E, Pianca N, Carpi A, Carullo P, Pesce P, Sacerdoti D, Sarais C, Catalucci D, Krüger M, Mongillo M, Sandri M. Zaglia T, et al. Among authors: sandri m. J Clin Invest. 2014 Jun;124(6):2410-24. doi: 10.1172/JCI66339. Epub 2014 May 1. J Clin Invest. 2014. PMID: 24789905 Free PMC article.
778 results