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Genetic Variation Determines PPARγ Function and Anti-diabetic Drug Response In Vivo.
Soccio RE, Chen ER, Rajapurkar SR, Safabakhsh P, Marinis JM, Dispirito JR, Emmett MJ, Briggs ER, Fang B, Everett LJ, Lim HW, Won KJ, Steger DJ, Wu Y, Civelek M, Voight BF, Lazar MA. Soccio RE, et al. Cell. 2015 Jul 2;162(1):33-44. doi: 10.1016/j.cell.2015.06.025. Cell. 2015. PMID: 26140591 Free PMC article.
Targeting PPARγ in the epigenome rescues genetic metabolic defects in mice.
Soccio RE, Li Z, Chen ER, Foong YH, Benson KK, Dispirito JR, Mullican SE, Emmett MJ, Briggs ER, Peed LC, Dzeng RK, Medina CJ, Jolivert JF, Kissig M, Rajapurkar SR, Damle M, Lim HW, Won KJ, Seale P, Steger DJ, Lazar MA. Soccio RE, et al. J Clin Invest. 2017 Apr 3;127(4):1451-1462. doi: 10.1172/JCI91211. Epub 2017 Feb 27. J Clin Invest. 2017. PMID: 28240605 Free PMC article.
Phosphorylated MED1 links transcription recycling and cancer growth.
Chen Z, Ye Z, Soccio RE, Nakadai T, Hankey W, Zhao Y, Huang F, Yuan F, Wang H, Cui Z, Sunkel B, Wu D, Dzeng RK, Thomas-Ahner JM, Huang THM, Clinton SK, Huang J, Lazar MA, Jin VX, Roeder RG, Wang Q. Chen Z, et al. Among authors: soccio re. Nucleic Acids Res. 2022 May 6;50(8):4450-4463. doi: 10.1093/nar/gkac246. Nucleic Acids Res. 2022. PMID: 35394046 Free PMC article.
Interrogation of nonconserved human adipose lincRNAs identifies a regulatory role of linc-ADAL in adipocyte metabolism.
Zhang X, Xue C, Lin J, Ferguson JF, Weiner A, Liu W, Han Y, Hinkle C, Li W, Jiang H, Gosai S, Hachet M, Garcia BA, Gregory BD, Soccio RE, Hogenesch JB, Seale P, Li M, Reilly MP. Zhang X, et al. Among authors: soccio re. Sci Transl Med. 2018 Jun 20;10(446):eaar5987. doi: 10.1126/scitranslmed.aar5987. Sci Transl Med. 2018. PMID: 29925637 Free PMC article.
28 results