Dodge M - Search Results

1

Identification of Oncogenic and Drug-Sensitizing Mutations in the Extracellular Domain of FGFR2.

Tanizaki J, Ercan D, Capelletti M, Dodge M, Xu C, Bahcall M, Tricker EM, Butaney M, Calles A, Sholl LM, Hammerman PS, Oxnard GR, Wong KK, Jänne PA. Tanizaki J, et al. Among authors: dodge m. Cancer Res. 2015 Aug 1;75(15):3139-46. doi: 10.1158/0008-5472.CAN-14-3771. Epub 2015 Jun 5. Cancer Res. 2015. PMID: 26048680

2

Identification of recurrent FGFR3-TACC3 fusion oncogenes from lung adenocarcinoma.

Capelletti M, Dodge ME, Ercan D, Hammerman PS, Park SI, Kim J, Sasaki H, Jablons DM, Lipson D, Young L, Stephens PJ, Miller VA, Lindeman NI, Munir KJ, Richards WG, Jänne PA. Capelletti M, et al. Among authors: dodge me. Clin Cancer Res. 2014 Dec 15;20(24):6551-8. doi: 10.1158/1078-0432.CCR-14-1337. Epub 2014 Oct 7. Clin Cancer Res. 2014. PMID: 25294908

3

Pharmacological targeting of the pseudokinase Her3.

Xie T, Lim SM, Westover KD, Dodge ME, Ercan D, Ficarro SB, Udayakumar D, Gurbani D, Tae HS, Riddle SM, Sim T, Marto JA, Jänne PA, Crews CM, Gray NS. Xie T, et al. Among authors: dodge me. Nat Chem Biol. 2014 Dec;10(12):1006-12. doi: 10.1038/nchembio.1658. Epub 2014 Oct 19. Nat Chem Biol. 2014. PMID: 25326665 Free PMC article.

4

Aldehyde dehydrogenase activity selects for lung adenocarcinoma stem cells dependent on notch signaling.

Sullivan JP, Spinola M, Dodge M, Raso MG, Behrens C, Gao B, Schuster K, Shao C, Larsen JE, Sullivan LA, Honorio S, Xie Y, Scaglioni PP, DiMaio JM, Gazdar AF, Shay JW, Wistuba II, Minna JD. Sullivan JP, et al. Among authors: dodge m. Cancer Res. 2010 Dec 1;70(23):9937-48. doi: 10.1158/0008-5472.CAN-10-0881. Epub 2010 Nov 30. Cancer Res. 2010. PMID: 21118965 Free PMC article.

5

Drugging the cancer stem cell compartment: lessons learned from the hedgehog and Wnt signal transduction pathways.

Dodge ME, Lum L. Dodge ME, et al. Annu Rev Pharmacol Toxicol. 2011;51:289-310. doi: 10.1146/annurev-pharmtox-010510-100558. Annu Rev Pharmacol Toxicol. 2011. PMID: 20887197 Free PMC article. Review.

6

Genome-wide RNAi screen reveals disease-associated genes that are common to Hedgehog and Wnt signaling.

Jacob LS, Wu X, Dodge ME, Fan CW, Kulak O, Chen B, Tang W, Wang B, Amatruda JF, Lum L. Jacob LS, et al. Sci Signal. 2011 Jan 25;4(157):ra4. doi: 10.1126/scisignal.2001225. Sci Signal. 2011. PMID: 21266715 Free PMC article.

7

Small molecule-mediated disruption of Wnt-dependent signaling in tissue regeneration and cancer.

Chen B, Dodge ME, Tang W, Lu J, Ma Z, Fan CW, Wei S, Hao W, Kilgore J, Williams NS, Roth MG, Amatruda JF, Chen C, Lum L. Chen B, et al. Nat Chem Biol. 2009 Feb;5(2):100-7. doi: 10.1038/nchembio.137. Epub 2009 Jan 4. Nat Chem Biol. 2009. PMID: 19125156 Free PMC article.

8

Tankyrase is necessary for canonical Wnt signaling during kidney development.

Karner CM, Merkel CE, Dodge M, Ma Z, Lu J, Chen C, Lum L, Carroll TJ. Karner CM, et al. Among authors: dodge m. Dev Dyn. 2010 Jul;239(7):2014-23. doi: 10.1002/dvdy.22340. Dev Dyn. 2010. PMID: 20549720 Free PMC article.

9

Diverse chemical scaffolds support direct inhibition of the membrane-bound O-acyltransferase porcupine.

Dodge ME, Moon J, Tuladhar R, Lu J, Jacob LS, Zhang LS, Shi H, Wang X, Moro E, Mongera A, Argenton F, Karner CM, Carroll TJ, Chen C, Amatruda JF, Lum L. Dodge ME, et al. J Biol Chem. 2012 Jun 29;287(27):23246-54. doi: 10.1074/jbc.M112.372029. Epub 2012 May 15. J Biol Chem. 2012. PMID: 22593577 Free PMC article.

10

A genome-wide RNAi screen for Wnt/beta-catenin pathway components identifies unexpected roles for TCF transcription factors in cancer.

Tang W, Dodge M, Gundapaneni D, Michnoff C, Roth M, Lum L. Tang W, et al. Among authors: dodge m. Proc Natl Acad Sci U S A. 2008 Jul 15;105(28):9697-702. doi: 10.1073/pnas.0804709105. Epub 2008 Jul 10. Proc Natl Acad Sci U S A. 2008. PMID: 18621708 Free PMC article.

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