Long L - Search Results

1

Selective enhancement of endothelial BMPR-II with BMP9 reverses pulmonary arterial hypertension.

Long L, Ormiston ML, Yang X, Southwood M, Gräf S, Machado RD, Mueller M, Kinzel B, Yung LM, Wilkinson JM, Moore SD, Drake KM, Aldred MA, Yu PB, Upton PD, Morrell NW. Long L, et al. Nat Med. 2015 Jul;21(7):777-85. doi: 10.1038/nm.3877. Epub 2015 Jun 15. Nat Med. 2015. PMID: 26076038 Free PMC article.

2

Dysfunctional Smad signaling contributes to abnormal smooth muscle cell proliferation in familial pulmonary arterial hypertension.

Yang X, Long L, Southwood M, Rudarakanchana N, Upton PD, Jeffery TK, Atkinson C, Chen H, Trembath RC, Morrell NW. Yang X, et al. Among authors: long l. Circ Res. 2005 May 27;96(10):1053-63. doi: 10.1161/01.RES.0000166926.54293.68. Epub 2005 Apr 21. Circ Res. 2005. PMID: 15845886

3

Mutations in bone morphogenetic protein type II receptor cause dysregulation of Id gene expression in pulmonary artery smooth muscle cells: implications for familial pulmonary arterial hypertension.

Yang J, Davies RJ, Southwood M, Long L, Yang X, Sobolewski A, Upton PD, Trembath RC, Morrell NW. Yang J, et al. Among authors: long l. Circ Res. 2008 May 23;102(10):1212-21. doi: 10.1161/CIRCRESAHA.108.173567. Epub 2008 Apr 24. Circ Res. 2008. PMID: 18436795

4

Expression of mutant BMPR-II in pulmonary endothelial cells promotes apoptosis and a release of factors that stimulate proliferation of pulmonary arterial smooth muscle cells.

Yang X, Long L, Reynolds PN, Morrell NW. Yang X, et al. Among authors: long l. Pulm Circ. 2011 Jan-Mar;1(1):103-10. doi: 10.4103/2045-8932.78100. Pulm Circ. 2011. PMID: 22034596 Free PMC article.

5

TNFα drives pulmonary arterial hypertension by suppressing the BMP type-II receptor and altering NOTCH signalling.

Hurst LA, Dunmore BJ, Long L, Crosby A, Al-Lamki R, Deighton J, Southwood M, Yang X, Nikolic MZ, Herrera B, Inman GJ, Bradley JR, Rana AA, Upton PD, Morrell NW. Hurst LA, et al. Among authors: long l. Nat Commun. 2017 Jan 13;8:14079. doi: 10.1038/ncomms14079. Nat Commun. 2017. PMID: 28084316 Free PMC article.

6

A Potential Role for Exosomal Translationally Controlled Tumor Protein Export in Vascular Remodeling in Pulmonary Arterial Hypertension.

Ferrer E, Dunmore BJ, Hassan D, Ormiston ML, Moore S, Deighton J, Long L, Yang XD, Stewart DJ, Morrell NW. Ferrer E, et al. Among authors: long l. Am J Respir Cell Mol Biol. 2018 Oct;59(4):467-478. doi: 10.1165/rcmb.2017-0129OC. Am J Respir Cell Mol Biol. 2018. PMID: 29676587 Free PMC article.

7

4PBA Restores Signaling of a Cysteine-substituted Mutant BMPR2 Receptor Found in Patients with Pulmonary Arterial Hypertension.

Dunmore BJ, Yang X, Crosby A, Moore S, Long L, Huang C, Southwood M, Austin ED, Rana A, Upton PD, Morrell NW. Dunmore BJ, et al. Among authors: long l. Am J Respir Cell Mol Biol. 2020 Aug;63(2):160-171. doi: 10.1165/rcmb.2019-0321OC. Am J Respir Cell Mol Biol. 2020. PMID: 32255665

8

Circulating BMP9 Protects the Pulmonary Endothelium during Inflammation-induced Lung Injury in Mice.

Li W, Long L, Yang X, Tong Z, Southwood M, King R, Caruso P, Upton PD, Yang P, Bocobo GA, Nikolic I, Higuera A, Salmon RM, Jiang H, Lodge KM, Hoenderdos K, Baron RM, Yu PB, Condliffe AM, Summers C, Nourshargh S, Chilvers ER, Morrell NW. Li W, et al. Among authors: long l. Am J Respir Crit Care Med. 2021 Jun 1;203(11):1419-1430. doi: 10.1164/rccm.202005-1761OC. Am J Respir Crit Care Med. 2021. PMID: 33320799 Free PMC article.

9

Impaired natural killer cell phenotype and function in idiopathic and heritable pulmonary arterial hypertension.

Ormiston ML, Chang C, Long LL, Soon E, Jones D, Machado R, Treacy C, Toshner MR, Campbell K, Riding A, Southwood M, Pepke-Zaba J, Exley A, Trembath RC, Colucci F, Wills M, Trowsdale J, Morrell NW. Ormiston ML, et al. Among authors: long ll. Circulation. 2012 Aug 28;126(9):1099-109. doi: 10.1161/CIRCULATIONAHA.112.110619. Epub 2012 Jul 25. Circulation. 2012. PMID: 22832786 Free article.

10

Differential effects of TGF-beta1 and BMP-4 on the hypoxic induction of cyclooxygenase-2 in human pulmonary artery smooth muscle cells.

Sheares KK, Jeffery TK, Long L, Yang X, Morrell NW. Sheares KK, et al. Among authors: long l. Am J Physiol Lung Cell Mol Physiol. 2004 Nov;287(5):L919-27. doi: 10.1152/ajplung.00012.2004. Epub 2004 Jun 25. Am J Physiol Lung Cell Mol Physiol. 2004. PMID: 15220111 Free article.

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