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Genome Analysis of Latin American Cervical Cancer: Frequent Activation of the PIK3CA Pathway.
Lou H, Villagran G, Boland JF, Im KM, Polo S, Zhou W, Odey U, Juárez-Torres E, Medina-Martínez I, Roman-Basaure E, Mitchell J, Roberson D, Sawitzke J, Garland L, Rodríguez-Herrera M, Wells D, Troyer J, Pinto FC, Bass S, Zhang X, Castillo M, Gold B, Morales H, Yeager M, Berumen J, Alvirez E, Gharzouzi E, Dean M. Lou H, et al. Clin Cancer Res. 2015 Dec 1;21(23):5360-70. doi: 10.1158/1078-0432.CCR-14-1837. Epub 2015 Jun 16. Clin Cancer Res. 2015. PMID: 26080840 Free PMC article.
The Amerindian mtDNA haplogroup B2 enhances the risk of HPV for cervical cancer: de-regulation of mitochondrial genes may be involved.
Guardado-Estrada M, Medina-Martínez I, Juárez-Torres E, Roman-Bassaure E, Macías L, Alfaro A, Alcántara-Vázquez A, Alonso P, Gomez G, Cruz-Talonia F, Serna L, Muñoz-Cortez S, Borges-Ibañez M, Espinosa A, Kofman S, Berumen J. Guardado-Estrada M, et al. J Hum Genet. 2012 Apr;57(4):269-76. doi: 10.1038/jhg.2012.17. Epub 2012 Feb 23. J Hum Genet. 2012. PMID: 22357541
Amplified genes may be overexpressed, unchanged, or downregulated in cervical cancer cell lines.
Vazquez-Mena O, Medina-Martinez I, Juárez-Torres E, Barrón V, Espinosa A, Villegas-Sepulveda N, Gómez-Laguna L, Nieto-Martínez K, Orozco L, Roman-Basaure E, Muñoz Cortez S, Borges Ibañez M, Venegas-Vega C, Guardado-Estrada M, Rangel-López A, Kofman S, Berumen J. Vazquez-Mena O, et al. PLoS One. 2012;7(3):e32667. doi: 10.1371/journal.pone.0032667. Epub 2012 Mar 7. PLoS One. 2012. PMID: 22412903 Free PMC article.
Impact of gene dosage on gene expression, biological processes and survival in cervical cancer: a genome-wide follow-up study.
Medina-Martinez I, Barrón V, Roman-Bassaure E, Juárez-Torres E, Guardado-Estrada M, Espinosa AM, Bermudez M, Fernández F, Venegas-Vega C, Orozco L, Zenteno E, Kofman S, Berumen J. Medina-Martinez I, et al. PLoS One. 2014 May 30;9(5):e97842. doi: 10.1371/journal.pone.0097842. eCollection 2014. PLoS One. 2014. PMID: 24879114 Free PMC article.
The mRNA and protein levels of the glycolytic enzymes lactate dehydrogenase A (LDHA) and phosphofructokinase platelet (PFKP) are good predictors of survival time, recurrence, and risk of death in cervical cancer patients.
Bolaños-Suárez V, Alfaro A, Espinosa AM, Medina-Martínez I, Juárez E, Villegas-Sepúlveda N, Gudiño-Zayas M, Gutiérrez-Castro A, Román-Bassaure E, Salinas-Nieves ME, Bruno-Muñoz S, Aranda C, Flores-Herrera O, Berumen J. Bolaños-Suárez V, et al. Among authors: medina martinez i. Cancer Med. 2023 Jul;12(14):15632-15649. doi: 10.1002/cam4.6123. Epub 2023 Jun 16. Cancer Med. 2023. PMID: 37326348 Free PMC article.
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