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Genomic analysis of diversity, population structure, virulence, and antimicrobial resistance in Klebsiella pneumoniae, an urgent threat to public health.
Holt KE, Wertheim H, Zadoks RN, Baker S, Whitehouse CA, Dance D, Jenney A, Connor TR, Hsu LY, Severin J, Brisse S, Cao H, Wilksch J, Gorrie C, Schultz MB, Edwards DJ, Nguyen KV, Nguyen TV, Dao TT, Mensink M, Minh VL, Nhu NT, Schultsz C, Kuntaman K, Newton PN, Moore CE, Strugnell RA, Thomson NR. Holt KE, et al. Among authors: thomson nr. Proc Natl Acad Sci U S A. 2015 Jul 7;112(27):E3574-81. doi: 10.1073/pnas.1501049112. Epub 2015 Jun 22. Proc Natl Acad Sci U S A. 2015. PMID: 26100894 Free PMC article.
Genome sequence of the enterobacterial phytopathogen Erwinia carotovora subsp. atroseptica and characterization of virulence factors.
Bell KS, Sebaihia M, Pritchard L, Holden MT, Hyman LJ, Holeva MC, Thomson NR, Bentley SD, Churcher LJ, Mungall K, Atkin R, Bason N, Brooks K, Chillingworth T, Clark K, Doggett J, Fraser A, Hance Z, Hauser H, Jagels K, Moule S, Norbertczak H, Ormond D, Price C, Quail MA, Sanders M, Walker D, Whitehead S, Salmond GP, Birch PR, Parkhill J, Toth IK. Bell KS, et al. Among authors: thomson nr. Proc Natl Acad Sci U S A. 2004 Jul 27;101(30):11105-10. doi: 10.1073/pnas.0402424101. Epub 2004 Jul 19. Proc Natl Acad Sci U S A. 2004. PMID: 15263089 Free PMC article.
Genomic plasticity of the causative agent of melioidosis, Burkholderia pseudomallei.
Holden MT, Titball RW, Peacock SJ, Cerdeño-Tárraga AM, Atkins T, Crossman LC, Pitt T, Churcher C, Mungall K, Bentley SD, Sebaihia M, Thomson NR, Bason N, Beacham IR, Brooks K, Brown KA, Brown NF, Challis GL, Cherevach I, Chillingworth T, Cronin A, Crossett B, Davis P, DeShazer D, Feltwell T, Fraser A, Hance Z, Hauser H, Holroyd S, Jagels K, Keith KE, Maddison M, Moule S, Price C, Quail MA, Rabbinowitsch E, Rutherford K, Sanders M, Simmonds M, Songsivilai S, Stevens K, Tumapa S, Vesaratchavest M, Whitehead S, Yeats C, Barrell BG, Oyston PC, Parkhill J. Holden MT, et al. Among authors: thomson nr. Proc Natl Acad Sci U S A. 2004 Sep 28;101(39):14240-5. doi: 10.1073/pnas.0403302101. Epub 2004 Sep 17. Proc Natl Acad Sci U S A. 2004. PMID: 15377794 Free PMC article.
The multidrug-resistant human pathogen Clostridium difficile has a highly mobile, mosaic genome.
Sebaihia M, Wren BW, Mullany P, Fairweather NF, Minton N, Stabler R, Thomson NR, Roberts AP, Cerdeño-Tárraga AM, Wang H, Holden MT, Wright A, Churcher C, Quail MA, Baker S, Bason N, Brooks K, Chillingworth T, Cronin A, Davis P, Dowd L, Fraser A, Feltwell T, Hance Z, Holroyd S, Jagels K, Moule S, Mungall K, Price C, Rabbinowitsch E, Sharp S, Simmonds M, Stevens K, Unwin L, Whithead S, Dupuy B, Dougan G, Barrell B, Parkhill J. Sebaihia M, et al. Among authors: thomson nr. Nat Genet. 2006 Jul;38(7):779-86. doi: 10.1038/ng1830. Epub 2006 Jun 25. Nat Genet. 2006. PMID: 16804543
Rapid Virulence Annotation (RVA): identification of virulence factors using a bacterial genome library and multiple invertebrate hosts.
Waterfield NR, Sanchez-Contreras M, Eleftherianos I, Dowling A, Yang G, Wilkinson P, Parkhill J, Thomson N, Reynolds SE, Bode HB, Dorus S, Ffrench-Constant RH. Waterfield NR, et al. Among authors: thomson n. Proc Natl Acad Sci U S A. 2008 Oct 14;105(41):15967-72. doi: 10.1073/pnas.0711114105. Epub 2008 Oct 6. Proc Natl Acad Sci U S A. 2008. PMID: 18838673 Free PMC article.
Variation in Salmonella enterica serovar typhi IncHI1 plasmids during the global spread of resistant typhoid fever.
Phan MD, Kidgell C, Nair S, Holt KE, Turner AK, Hinds J, Butcher P, Cooke FJ, Thomson NR, Titball R, Bhutta ZA, Hasan R, Dougan G, Wain J. Phan MD, et al. Among authors: thomson nr. Antimicrob Agents Chemother. 2009 Feb;53(2):716-27. doi: 10.1128/AAC.00645-08. Epub 2008 Nov 17. Antimicrob Agents Chemother. 2009. PMID: 19015365 Free PMC article.
345 results