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Granulomonocytic progenitors are key target cells of azacytidine in higher risk myelodysplastic syndromes and acute myeloid leukemia.
Ali A, Penneroux J, Dal Bello R Jr, Massé A, Quentin S, Unnikrishnan A, Hernandez L, Raffoux E, Ben Abdelali R, Renneville A, Preudhomme C, Pimanda J, Dombret H, Soulier J, Fenaux P, Clappier E, Adès L, Puissant A, Itzykson R. Ali A, et al. Leukemia. 2018 Aug;32(8):1856-1860. doi: 10.1038/s41375-018-0076-2. Epub 2018 Feb 26. Leukemia. 2018. PMID: 29535430 No abstract available.
BET inhibitors impair leukemic stem cell function only in defined oncogenic subgroups of acute myeloid leukaemias.
Massé A, Roulin L, Pasanisi J, Penneroux J, Gachet S, Delord M, Ali A, Alberdi A, Berrou J, Passet M, Hernandez L, Quentin S, Gardin C, Raffoux E, Adès L, Braun T, Soulier J, Clappier E, Dombret H, Puissant A, Itzykson R. Massé A, et al. Among authors: ali a. Leuk Res. 2019 Dec;87:106269. doi: 10.1016/j.leukres.2019.106269. Epub 2019 Nov 7. Leuk Res. 2019. PMID: 31751766
Critical role of the HDAC6-cortactin axis in human megakaryocyte maturation leading to a proplatelet-formation defect.
Messaoudi K, Ali A, Ishaq R, Palazzo A, Sliwa D, Bluteau O, Souquère S, Muller D, Diop KM, Rameau P, Lapierre V, Marolleau JP, Matthias P, Godin I, Pierron G, Thomas SG, Watson SP, Droin N, Vainchenker W, Plo I, Raslova H, Debili N. Messaoudi K, et al. Among authors: ali a. Nat Commun. 2017 Nov 27;8(1):1786. doi: 10.1038/s41467-017-01690-2. Nat Commun. 2017. PMID: 29176689 Free PMC article.
Thrombocytopenia induced by the histone deacetylase inhibitor abexinostat involves p53-dependent and -independent mechanisms.
Ali A, Bluteau O, Messaoudi K, Palazzo A, Boukour S, Lordier L, Lecluse Y, Rameau P, Kraus-Berthier L, Jacquet-Bescond A, Lelièvre H, Depil S, Dessen P, Solary E, Raslova H, Vainchenker W, Plo I, Debili N. Ali A, et al. Cell Death Dis. 2013 Jul 25;4(7):e738. doi: 10.1038/cddis.2013.260. Cell Death Dis. 2013. PMID: 23887629 Free PMC article.
Expertise in surgical neuro-oncology. Results of a survey by the EANS neuro-oncology section.
Gousias K, Hoyer A, Mazurczyk LA, Bartek J Jr, Bruneau M, Celtikci E, Foroglou N, Freyschlag C, Grossman R, Jungk C, Metellus P, Netuka D, Rola R, Schucht P, Senft C, Signorelli F, Vincent AJPE, Simon M; EANS Surgical Neuro-oncology Expertise Survey working group. Gousias K, et al. Brain Spine. 2024 May 7;4:102822. doi: 10.1016/j.bas.2024.102822. eCollection 2024. Brain Spine. 2024. PMID: 38831935 Free PMC article.
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