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Genome-wide burden of deleterious coding variants increased in schizophrenia.
Loohuis LMO, Vorstman JAS, Ori AP, Staats KA, Wang T, Richards AL, Leonenko G, Walters JT, DeYoung J; GROUP consortium; Cantor RM, Ophoff RA. Loohuis LMO, et al. Among authors: vorstman jas. Nat Commun. 2015 Jul 9;6:7501. doi: 10.1038/ncomms8501. Nat Commun. 2015. PMID: 26158538 Free PMC article.
Proline affects brain function in 22q11DS children with the low activity COMT 158 allele.
Vorstman JA, Turetsky BI, Sijmens-Morcus ME, de Sain MG, Dorland B, Sprong M, Rappaport EF, Beemer FA, Emanuel BS, Kahn RS, van Engeland H, Kemner C. Vorstman JA, et al. Neuropsychopharmacology. 2009 Feb;34(3):739-46. doi: 10.1038/npp.2008.132. Epub 2008 Sep 3. Neuropsychopharmacology. 2009. PMID: 18769474 Free PMC article.
Gene-network analysis identifies susceptibility genes related to glycobiology in autism.
van der Zwaag B, Franke L, Poot M, Hochstenbach R, Spierenburg HA, Vorstman JA, van Daalen E, de Jonge MV, Verbeek NE, Brilstra EH, van 't Slot R, Ophoff RA, van Es MA, Blauw HM, Veldink JH, Buizer-Voskamp JE, Beemer FA, van den Berg LH, Wijmenga C, van Amstel HK, van Engeland H, Burbach JP, Staal WG. van der Zwaag B, et al. PLoS One. 2009 May 28;4(5):e5324. doi: 10.1371/journal.pone.0005324. PLoS One. 2009. PMID: 19492091 Free PMC article.
A double hit implicates DIAPH3 as an autism risk gene.
Vorstman JA, van Daalen E, Jalali GR, Schmidt ER, Pasterkamp RJ, de Jonge M, Hennekam EA, Janson E, Staal WG, van der Zwaag B, Burbach JP, Kahn RS, Emanuel BS, van Engeland H, Ophoff RA. Vorstman JA, et al. Mol Psychiatry. 2011 Apr;16(4):442-51. doi: 10.1038/mp.2010.26. Epub 2010 Mar 23. Mol Psychiatry. 2011. PMID: 20308993 Free PMC article.
116 results