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Homozygous loss-of-function variants in European cosmopolitan and isolate populations.
Kaiser VB, Svinti V, Prendergast JG, Chau YY, Campbell A, Patarcic I, Barroso I, Joshi PK, Hastie ND, Miljkovic A, Taylor MS; Generation Scotland; UK10K; Enroth S, Memari Y, Kolb-Kokocinski A, Wright AF, Gyllensten U, Durbin R, Rudan I, Campbell H, Polašek O, Johansson Å, Sauer S, Porteous DJ, Fraser RM, Drake C, Vitart V, Hayward C, Semple CA, Wilson JF. Kaiser VB, et al. Among authors: chau yy. Hum Mol Genet. 2015 Oct 1;24(19):5464-74. doi: 10.1093/hmg/ddv272. Epub 2015 Jul 14. Hum Mol Genet. 2015. PMID: 26173456 Free PMC article.
WT1 regulates the expression of inhibitory chemokines during heart development.
Velecela V, Lettice LA, Chau YY, Slight J, Berry RL, Thornburn A, Gunst QD, van den Hoff M, Reina M, Martínez FO, Hastie ND, Martínez-Estrada OM. Velecela V, et al. Among authors: chau yy. Hum Mol Genet. 2013 Dec 20;22(25):5083-95. doi: 10.1093/hmg/ddt358. Epub 2013 Jul 29. Hum Mol Genet. 2013. PMID: 23900076
Acute multiple organ failure in adult mice deleted for the developmental regulator Wt1.
Chau YY, Brownstein D, Mjoseng H, Lee WC, Buza-Vidas N, Nerlov C, Jacobsen SE, Perry P, Berry R, Thornburn A, Sexton D, Morton N, Hohenstein P, Freyer E, Samuel K, van't Hof R, Hastie N. Chau YY, et al. PLoS Genet. 2011 Dec;7(12):e1002404. doi: 10.1371/journal.pgen.1002404. Epub 2011 Dec 22. PLoS Genet. 2011. PMID: 22216009 Free PMC article.
Epicardial cell shape and maturation are regulated by Wt1 via transcriptional control of Bmp4.
Velecela V, Torres-Cano A, García-Melero A, Ramiro-Pareta M, Müller-Sánchez C, Segarra-Mondejar M, Chau YY, Campos-Bonilla B, Reina M, Soriano FX, Hastie ND, Martínez FO, Martínez-Estrada OM. Velecela V, et al. Among authors: chau yy. Development. 2019 Oct 17;146(20):dev178723. doi: 10.1242/dev.178723. Development. 2019. PMID: 31624071
Editorial: WT1 in Development and Disease.
Chau YY, Martínez-Estrada OM. Chau YY, et al. Front Cell Dev Biol. 2022 Jul 8;10:969100. doi: 10.3389/fcell.2022.969100. eCollection 2022. Front Cell Dev Biol. 2022. PMID: 35874805 Free PMC article. No abstract available.
26 results