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Optogenetic determination of the myocardial requirements for extrasystoles by cell type-specific targeting of ChannelRhodopsin-2.
Zaglia T, Pianca N, Borile G, Da Broi F, Richter C, Campione M, Lehnart SE, Luther S, Corrado D, Miquerol L, Mongillo M. Zaglia T, et al. Among authors: lehnart se. Proc Natl Acad Sci U S A. 2015 Aug 11;112(32):E4495-504. doi: 10.1073/pnas.1509380112. Epub 2015 Jul 23. Proc Natl Acad Sci U S A. 2015. PMID: 26204914 Free PMC article.
Stimulated emission depletion live-cell super-resolution imaging shows proliferative remodeling of T-tubule membrane structures after myocardial infarction.
Wagner E, Lauterbach MA, Kohl T, Westphal V, Williams GS, Steinbrecher JH, Streich JH, Korff B, Tuan HT, Hagen B, Luther S, Hasenfuss G, Parlitz U, Jafri MS, Hell SW, Lederer WJ, Lehnart SE. Wagner E, et al. Among authors: lehnart se. Circ Res. 2012 Aug 3;111(4):402-14. doi: 10.1161/CIRCRESAHA.112.274530. Epub 2012 Jun 21. Circ Res. 2012. PMID: 22723297 Free PMC article.
Sensing Cardiac Electrical Activity With a Cardiac Myocyte--Targeted Optogenetic Voltage Indicator.
Chang Liao ML, de Boer TP, Mutoh H, Raad N, Richter C, Wagner E, Downie BR, Unsöld B, Arooj I, Streckfuss-Bömeke K, Döker S, Luther S, Guan K, Wagner S, Lehnart SE, Maier LS, Stühmer W, Wettwer E, van Veen T, Morlock MM, Knöpfel T, Zimmermann WH. Chang Liao ML, et al. Among authors: lehnart se. Circ Res. 2015 Aug 14;117(5):401-12. doi: 10.1161/CIRCRESAHA.117.306143. Epub 2015 Jun 15. Circ Res. 2015. PMID: 26078285
Sarcoplasmic reticulum calcium leak contributes to arrhythmia but not to heart failure progression.
Mohamed BA, Hartmann N, Tirilomis P, Sekeres K, Li W, Neef S, Richter C, Zeisberg EM, Kattner L, Didié M, Guan K, Schmitto JD, Lehnart SE, Luther S, Voigt N, Seidler T, Sossalla S, Hasenfuss G, Toischer K. Mohamed BA, et al. Among authors: lehnart se. Sci Transl Med. 2018 Sep 12;10(458):eaan0724. doi: 10.1126/scitranslmed.aan0724. Sci Transl Med. 2018. PMID: 30209242
Resolving titin's lifecycle and the spatial organization of protein turnover in mouse cardiomyocytes.
Rudolph F, Hüttemeister J, da Silva Lopes K, Jüttner R, Yu L, Bergmann N, Friedrich D, Preibisch S, Wagner E, Lehnart SE, Gregorio CC, Gotthardt M. Rudolph F, et al. Among authors: lehnart se. Proc Natl Acad Sci U S A. 2019 Dec 10;116(50):25126-25136. doi: 10.1073/pnas.1904385116. Epub 2019 Nov 22. Proc Natl Acad Sci U S A. 2019. PMID: 31757849 Free PMC article.
Novel Optics-Based Approaches for Cardiac Electrophysiology: A Review.
Müllenbroich MC, Kelly A, Acker C, Bub G, Bruegmann T, Di Bona A, Entcheva E, Ferrantini C, Kohl P, Lehnart SE, Mongillo M, Parmeggiani C, Richter C, Sasse P, Zaglia T, Sacconi L, Smith GL. Müllenbroich MC, et al. Among authors: lehnart se. Front Physiol. 2021 Nov 18;12:769586. doi: 10.3389/fphys.2021.769586. eCollection 2021. Front Physiol. 2021. PMID: 34867476 Free PMC article. Review.
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