Kraynak AR - Search Results

1

Alkaline comet assay in liver and stomach, and micronucleus assay in bone marrow, from rats treated with 2-acetylaminofluorene, azidothymidine, cisplatin, or isobutyraldehyde.

Kraynak AR, Barnum JE, Cunningham CL, Ng A, Ykoruk BA, Bennet B, Stoffregen D, Merschman M, Freeland E, Galloway SM. Kraynak AR, et al. Mutat Res Genet Toxicol Environ Mutagen. 2015 Jul;786-788:77-86. doi: 10.1016/j.mrgentox.2015.03.005. Epub 2015 Mar 5. Mutat Res Genet Toxicol Environ Mutagen. 2015. PMID: 26212296

2

Validation of a high-throughput in vitro alkaline elution/rat hepatocyte assay for DNA damage.

Gealy R, Wright-Bourque JL, Kraynak AR, McKelvey TW, Barnum JE, Storer RD. Gealy R, et al. Among authors: kraynak ar. Mutat Res. 2007 Apr 20;629(1):49-63. doi: 10.1016/j.mrgentox.2007.01.005. Epub 2007 Jan 20. Mutat Res. 2007. PMID: 17306613

3

Rapid DNA degradation in primary rat hepatocytes treated with diverse cytotoxic chemicals: analysis by pulsed field gel electrophoresis and implications for alkaline elution assays.

Elia MC, Storer RD, McKelvey TW, Kraynak AR, Barnum JE, Harmon LS, DeLuca JG, Nichols WW. Elia MC, et al. Among authors: kraynak ar. Environ Mol Mutagen. 1994;24(3):181-91. doi: 10.1002/em.2850240307. Environ Mol Mutagen. 1994. PMID: 7957122

4

Revalidation of the in vitro alkaline elution/rat hepatocyte assay for DNA damage: improved criteria for assessment of cytotoxicity and genotoxicity and results for 81 compounds.

Storer RD, McKelvey TW, Kraynak AR, Elia MC, Barnum JE, Harmon LS, Nichols WW, DeLuca JG. Storer RD, et al. Among authors: kraynak ar. Mutat Res. 1996 Jun 12;368(2):59-101. doi: 10.1016/0165-1218(95)00070-4. Mutat Res. 1996. PMID: 8684406

5

Predictions of genotoxic potential, mode of action, molecular targets, and potency via a tiered multiflow® assay data analysis strategy.

Dertinger SD, Kraynak AR, Wheeldon RP, Bernacki DT, Bryce SM, Hall N, Bemis JC, Galloway SM, Escobar PA, Johnson GE. Dertinger SD, et al. Among authors: kraynak ar. Environ Mol Mutagen. 2019 Jul;60(6):513-533. doi: 10.1002/em.22274. Epub 2019 Feb 27. Environ Mol Mutagen. 2019. PMID: 30702769 Free PMC article.

6

JaCVAM-organized international validation study of the in vivo rodent alkaline comet assay for the detection of genotoxic carcinogens: I. Summary of pre-validation study results.

Uno Y, Kojima H, Omori T, Corvi R, Honma M, Schechtman LM, Tice RR, Burlinson B, Escobar PA, Kraynak AR, Nakagawa Y, Nakajima M, Pant K, Asano N, Lovell D, Morita T, Ohno Y, Hayashi M. Uno Y, et al. Among authors: kraynak ar. Mutat Res Genet Toxicol Environ Mutagen. 2015 Jul;786-788:3-13. doi: 10.1016/j.mrgentox.2015.04.011. Epub 2015 May 5. Mutat Res Genet Toxicol Environ Mutagen. 2015. PMID: 26212293

7

Collaborative study on fifteen compounds in the rat-liver Comet assay integrated into 2- and 4-week repeat-dose studies.

Rothfuss A, O'Donovan M, De Boeck M, Brault D, Czich A, Custer L, Hamada S, Plappert-Helbig U, Hayashi M, Howe J, Kraynak AR, van der Leede BJ, Nakajima M, Priestley C, Thybaud V, Saigo K, Sawant S, Shi J, Storer R, Struwe M, Vock E, Galloway S. Rothfuss A, et al. Among authors: kraynak ar. Mutat Res. 2010 Sep 30;702(1):40-69. doi: 10.1016/j.mrgentox.2010.07.006. Epub 2010 Jul 23. Mutat Res. 2010. PMID: 20656055

8

JaCVAM-organized international validation study of the in vivo rodent alkaline comet assay for detection of genotoxic carcinogens: II. Summary of definitive validation study results.

Uno Y, Kojima H, Omori T, Corvi R, Honma M, Schechtman LM, Tice RR, Beevers C, De Boeck M, Burlinson B, Hobbs CA, Kitamoto S, Kraynak AR, McNamee J, Nakagawa Y, Pant K, Plappert-Helbig U, Priestley C, Takasawa H, Wada K, Wirnitzer U, Asano N, Escobar PA, Lovell D, Morita T, Nakajima M, Ohno Y, Hayashi M. Uno Y, et al. Among authors: kraynak ar. Mutat Res Genet Toxicol Environ Mutagen. 2015 Jul;786-788:45-76. doi: 10.1016/j.mrgentox.2015.04.010. Epub 2015 Apr 29. Mutat Res Genet Toxicol Environ Mutagen. 2015. PMID: 26212295

9

Effects of high osmotic strength on chromosome aberrations, sister-chromatid exchanges and DNA strand breaks, and the relation to toxicity.

Galloway SM, Deasy DA, Bean CL, Kraynak AR, Armstrong MJ, Bradley MO. Galloway SM, et al. Among authors: kraynak ar. Mutat Res. 1987 Sep;189(1):15-25. doi: 10.1016/0165-1218(87)90029-2. Mutat Res. 1987. PMID: 3627148

10

Cytotoxicity as measured by trypan blue as a potentially confounding variable in the in vitro alkaline elution/rat hepatocyte assay.

Elia MC, Storer RD, Harmon LS, Kraynak AR, McKelvey TW, Hertzog PR, Keenan KP, DeLuca JG, Nichols WW. Elia MC, et al. Among authors: kraynak ar. Mutat Res. 1993 Jun;291(3):193-205. doi: 10.1016/0165-1161(93)90159-w. Mutat Res. 1993. PMID: 7685060

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