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NOTCH1 mutations occur early during cutaneous squamous cell carcinogenesis.
South AP, Purdie KJ, Watt SA, Haldenby S, den Breems N, Dimon M, Arron ST, Kluk MJ, Aster JC, McHugh A, Xue DJ, Dayal JH, Robinson KS, Rizvi SH, Proby CM, Harwood CA, Leigh IM. South AP, et al. J Invest Dermatol. 2014 Oct;134(10):2630-2638. doi: 10.1038/jid.2014.154. Epub 2014 Mar 24. J Invest Dermatol. 2014. PMID: 24662767 Free PMC article.
CREBBP mutation in human cutaneous squamous cell carcinoma.
Watt SA, Purdie KJ, den Breems NY, Dimon M, Tucker S, Arron ST, McHugh A, Xue DJ, Dayal JH, Harwood CA, Leigh IM, Proby CM, South AP. Watt SA, et al. Exp Dermatol. 2016 Aug;25(8):650-1. doi: 10.1111/exd.13044. Epub 2016 Jun 30. Exp Dermatol. 2016. PMID: 27094574 No abstract available.
Inactivation of TGFβ receptors in stem cells drives cutaneous squamous cell carcinoma.
Cammareri P, Rose AM, Vincent DF, Wang J, Nagano A, Libertini S, Ridgway RA, Athineos D, Coates PJ, McHugh A, Pourreyron C, Dayal JH, Larsson J, Weidlich S, Spender LC, Sapkota GP, Purdie KJ, Proby CM, Harwood CA, Leigh IM, Clevers H, Barker N, Karlsson S, Pritchard C, Marais R, Chelala C, South AP, Sansom OJ, Inman GJ. Cammareri P, et al. Nat Commun. 2016 Aug 25;7:12493. doi: 10.1038/ncomms12493. Nat Commun. 2016. PMID: 27558455 Free PMC article.
NT5E (CD73) is epigenetically regulated in malignant melanoma and associated with metastatic site specificity.
Wang H, Lee S, Nigro CL, Lattanzio L, Merlano M, Monteverde M, Matin R, Purdie K, Mladkova N, Bergamaschi D, Harwood C, Syed N, Szlosarek P, Briasoulis E, McHugh A, Thompson A, Evans A, Leigh I, Fleming C, Inman GJ, Hatzimichael E, Proby C, Crook T. Wang H, et al. Br J Cancer. 2012 Apr 10;106(8):1446-52. doi: 10.1038/bjc.2012.95. Epub 2012 Mar 27. Br J Cancer. 2012. PMID: 22454080 Free PMC article.
NT5E CpG island methylation is a favourable breast cancer biomarker.
Lo Nigro C, Monteverde M, Lee S, Lattanzio L, Vivenza D, Comino A, Syed N, McHugh A, Wang H, Proby C, Garrone O, Merlano M, Hatzimichael E, Briasoulis E, Gojis O, Palmieri C, Jordan L, Quinlan P, Thompson A, Crook T. Lo Nigro C, et al. Br J Cancer. 2012 Jun 26;107(1):75-83. doi: 10.1038/bjc.2012.212. Epub 2012 May 31. Br J Cancer. 2012. PMID: 22653144 Free PMC article.
15 results