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Release of Active Peptidyl Arginine Deiminases by Neutrophils Can Explain Production of Extracellular Citrullinated Autoantigens in Rheumatoid Arthritis Synovial Fluid.
Spengler J, Lugonja B, Ytterberg AJ, Zubarev RA, Creese AJ, Pearson MJ, Grant MM, Milward M, Lundberg K, Buckley CD, Filer A, Raza K, Cooper PR, Chapple IL, Scheel-Toellner D. Spengler J, et al. Among authors: ytterberg aj. Arthritis Rheumatol. 2015 Dec;67(12):3135-45. doi: 10.1002/art.39313. Arthritis Rheumatol. 2015. PMID: 26245941 Free PMC article.
IgG antibodies to cyclic citrullinated peptides exhibit profiles specific in terms of IgG subclasses, Fc-glycans and a fab-Peptide sequence.
Lundström SL, Fernandes-Cerqueira C, Ytterberg AJ, Ossipova E, Hensvold AH, Jakobsson PJ, Malmström V, Catrina AI, Klareskog L, Lundberg K, Zubarev RA. Lundström SL, et al. Among authors: ytterberg aj. PLoS One. 2014 Nov 26;9(11):e113924. doi: 10.1371/journal.pone.0113924. eCollection 2014. PLoS One. 2014. PMID: 25426976 Free PMC article.
Antibodies to carbamylated α-enolase epitopes in rheumatoid arthritis also bind citrullinated epitopes and are largely indistinct from anti-citrullinated protein antibodies.
Reed E, Jiang X, Kharlamova N, Ytterberg AJ, Catrina AI, Israelsson L, Mathsson-Alm L, Hansson M, Alfredsson L, Rönnelid J, Lundberg K. Reed E, et al. Among authors: ytterberg aj. Arthritis Res Ther. 2016 May 4;18(1):96. doi: 10.1186/s13075-016-1001-6. Arthritis Res Ther. 2016. PMID: 27145822 Free PMC article.
Autoreactivity to malondialdehyde-modifications in rheumatoid arthritis is linked to disease activity and synovial pathogenesis.
Grönwall C, Amara K, Hardt U, Krishnamurthy A, Steen J, Engström M, Sun M, Ytterberg AJ, Zubarev RA, Scheel-Toellner D, Greenberg JD, Klareskog L, Catrina AI, Malmström V, Silverman GJ. Grönwall C, et al. Among authors: ytterberg aj. J Autoimmun. 2017 Nov;84:29-45. doi: 10.1016/j.jaut.2017.06.004. Epub 2017 Jun 21. J Autoimmun. 2017. PMID: 28647488
Shared immunological targets in the lungs and joints of patients with rheumatoid arthritis: identification and validation.
Ytterberg AJ, Joshua V, Reynisdottir G, Tarasova NK, Rutishauser D, Ossipova E, Haj Hensvold A, Eklund A, Sköld CM, Grunewald J, Malmström V, Jakobsson PJ, Rönnelid J, Padyukov L, Zubarev RA, Klareskog L, Catrina AI. Ytterberg AJ, et al. Ann Rheum Dis. 2015 Sep;74(9):1772-7. doi: 10.1136/annrheumdis-2013-204912. Epub 2014 May 9. Ann Rheum Dis. 2015. PMID: 24817415
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