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EZH2 is increased in paediatric T-cell acute lymphoblastic leukemia and is a suitable molecular target in combination treatment approaches.
D'Angelo V, Iannotta A, Ramaglia M, Lombardi A, Zarone MR, Desiderio V, Affinita MC, Pecoraro G, Di Martino M, Indolfi P, Casale F, Caraglia M. D'Angelo V, et al. Among authors: affinita mc. J Exp Clin Cancer Res. 2015 Aug 14;34(1):83. doi: 10.1186/s13046-015-0191-0. J Exp Clin Cancer Res. 2015. PMID: 26268310 Free PMC article.
Methotrexate toxicity and efficacy during the consolidation phase in paediatric acute lymphoblastic leukaemia and MTHFR polymorphisms as pharmacogenetic determinants.
D'Angelo V, Ramaglia M, Iannotta A, Crisci S, Indolfi P, Francese M, Affinita MC, Pecoraro G, Napolitano A, Fusco C, Oreste M, Indolfi C, Casale F. D'Angelo V, et al. Among authors: affinita mc. Cancer Chemother Pharmacol. 2011 Nov;68(5):1339-46. doi: 10.1007/s00280-011-1665-1. Epub 2011 May 18. Cancer Chemother Pharmacol. 2011. PMID: 21590445
Influence of methylenetetrahydrofolate reductase gene polymorphisms on the outcome of pediatric patients with non-Hodgkin lymphoma treated with high-dose methotrexate.
D'Angelo V, Ramaglia M, Iannotta A, Francese M, Pota E, Affinita MC, Pecoraro G, Indolfi C, Di Martino M, Di Pinto D, Buffardi S, Poggi V, Indolfi P, Casale F. D'Angelo V, et al. Among authors: affinita mc. Leuk Lymphoma. 2013 Dec;54(12):2639-44. doi: 10.3109/10428194.2013.784758. Epub 2013 Apr 19. Leuk Lymphoma. 2013. PMID: 23488607
Pediatric nonrhabdomyosarcoma soft tissue sarcomas arising at visceral sites.
Ferrari A, Magni C, Bergamaschi L, Cecchetto G, Alaggio R, Milano GM, Bertolini P, Basso E, Manzitti C, Di Martino M, Giurici N, Melchionda F, Cecinati V, Chiaravalli S, Affinita MC, Scagnellato A, Casanova M, Bisogno G. Ferrari A, et al. Among authors: affinita mc. Pediatr Blood Cancer. 2017 Sep;64(9). doi: 10.1002/pbc.26490. Epub 2017 Feb 24. Pediatr Blood Cancer. 2017. PMID: 28233470
Salvage rates and prognostic factors after relapse in children and adolescents with malignant peripheral nerve sheath tumors.
Bergamaschi L, Bisogno G, Manzitti C, D'Angelo P, Milano GM, Scagnellato A, Cappelletti M, Chiaravalli S, Dall'Igna P, Alaggio R, Ruggiero A, Di Martino M, Affinita MC, Pierobon M, Garaventa A, Casanova M, Ferrari A. Bergamaschi L, et al. Among authors: affinita mc. Pediatr Blood Cancer. 2018 Feb;65(2). doi: 10.1002/pbc.26816. Epub 2017 Sep 19. Pediatr Blood Cancer. 2018. PMID: 28926683 Clinical Trial.
Biliary tract rhabdomyosarcoma: a report from the Soft Tissue Sarcoma Committee of the Associazione Italiana Ematologia Oncologia Pediatrica.
Perruccio K, Cecinati V, Scagnellato A, Provenzi M, Milano GM, Basso E, Manzitti C, Cecchetto G, Alaggio R, Di Martino M, Schiavetti A, Melchionda F, Affinita MC, Chiaravalli S, Miglionico L, Balter R, Tamburini A, Bisogno G, Ferrari A. Perruccio K, et al. Among authors: affinita mc. Tumori. 2018 Jun;104(3):232-237. doi: 10.5301/tj.5000692. Epub 2018 May 8. Tumori. 2018. PMID: 29192742
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