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Perturbation biology nominates upstream-downstream drug combinations in RAF inhibitor resistant melanoma cells.
Elife. 2015 Aug 18;4:e04640. doi: 10.7554/eLife.04640.
Elife. 2015.
PMID: 26284497
Free PMC article.
Perturbation biology: inferring signaling networks in cellular systems.
Molinelli EJ, Korkut A, Wang W, Miller ML, Gauthier NP, Jing X, Kaushik P, He Q, Mills G, Solit DB, Pratilas CA, Weigt M, Braunstein A, Pagnani A, Zecchina R, Sander C.
Molinelli EJ, et al.
PLoS Comput Biol. 2013;9(12):e1003290. doi: 10.1371/journal.pcbi.1003290. Epub 2013 Dec 19.
PLoS Comput Biol. 2013.
PMID: 24367245
Free PMC article.
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Drug synergy screen and network modeling in dedifferentiated liposarcoma identifies CDK4 and IGF1R as synergistic drug targets.
Miller ML, Molinelli EJ, Nair JS, Sheikh T, Samy R, Jing X, He Q, Korkut A, Crago AM, Singer S, Schwartz GK, Sander C.
Miller ML, et al. Among authors: molinelli ej.
Sci Signal. 2013 Sep 24;6(294):ra85. doi: 10.1126/scisignal.2004014.
Sci Signal. 2013.
PMID: 24065146
Free PMC article.
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Spatial normalization of reverse phase protein array data.
Kaushik P, Molinelli EJ, Miller ML, Wang W, Korkut A, Liu W, Ju Z, Lu Y, Mills G, Sander C.
Kaushik P, et al. Among authors: molinelli ej.
PLoS One. 2014 Dec 12;9(12):e97213. doi: 10.1371/journal.pone.0097213. eCollection 2014.
PLoS One. 2014.
PMID: 25501559
Free PMC article.
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Integrin-α10 Dependency Identifies RAC and RICTOR as Therapeutic Targets in High-Grade Myxofibrosarcoma.
Okada T, Lee AY, Qin LX, Agaram N, Mimae T, Shen Y, O'Connor R, López-Lago MA, Craig A, Miller ML, Agius P, Molinelli E, Socci ND, Crago AM, Shima F, Sander C, Singer S.
Okada T, et al.
Cancer Discov. 2016 Oct;6(10):1148-1165. doi: 10.1158/2159-8290.CD-15-1481. Epub 2016 Aug 30.
Cancer Discov. 2016.
PMID: 27577794
Free PMC article.
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Modeling local and global intracellular calcium responses mediated by diffusely distributed inositol 1,4,5-trisphosphate receptors.
Williams GS, Molinelli EJ, Smith GD.
Williams GS, et al. Among authors: molinelli ej.
J Theor Biol. 2008 Jul 7;253(1):170-88. doi: 10.1016/j.jtbi.2008.02.040. Epub 2008 Mar 6.
J Theor Biol. 2008.
PMID: 18405920
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