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Sirtuin1 Suppresses Osteoclastogenesis by Deacetylating FoxOs.
Kim HN, Han L, Iyer S, de Cabo R, Zhao H, O'Brien CA, Manolagas SC, Almeida M. Kim HN, et al. Among authors: iyer s. Mol Endocrinol. 2015 Oct;29(10):1498-509. doi: 10.1210/me.2015-1133. Epub 2015 Aug 19. Mol Endocrinol. 2015. PMID: 26287518 Free PMC article.
FOXOs attenuate bone formation by suppressing Wnt signaling.
Iyer S, Ambrogini E, Bartell SM, Han L, Roberson PK, de Cabo R, Jilka RL, Weinstein RS, O'Brien CA, Manolagas SC, Almeida M. Iyer S, et al. J Clin Invest. 2013 Aug;123(8):3409-19. doi: 10.1172/JCI68049. Epub 2013 Jul 15. J Clin Invest. 2013. PMID: 23867625 Free PMC article.
The Role of FoxOs in Bone Health and Disease.
Kim HN, Iyer S, Ring R, Almeida M. Kim HN, et al. Among authors: iyer s. Curr Top Dev Biol. 2018;127:149-163. doi: 10.1016/bs.ctdb.2017.10.004. Epub 2017 Dec 14. Curr Top Dev Biol. 2018. PMID: 29433736 Review.
Estrogens decrease osteoclast number by attenuating mitochondria oxidative phosphorylation and ATP production in early osteoclast precursors.
Kim HN, Ponte F, Nookaew I, Ucer Ozgurel S, Marques-Carvalho A, Iyer S, Warren A, Aykin-Burns N, Krager K, Sardao VA, Han L, de Cabo R, Zhao H, Jilka RL, Manolagas SC, Almeida M. Kim HN, et al. Among authors: iyer s. Sci Rep. 2020 Jul 20;10(1):11933. doi: 10.1038/s41598-020-68890-7. Sci Rep. 2020. PMID: 32686739 Free PMC article.
2,409 results