Rhee KY - Search Results

1

Targeting Mycobacterium tuberculosis Biotin Protein Ligase (MtBPL) with Nucleoside-Based Bisubstrate Adenylation Inhibitors.

Bockman MR, Kalinda AS, Petrelli R, De la Mora-Rey T, Tiwari D, Liu F, Dawadi S, Nandakumar M, Rhee KY, Schnappinger D, Finzel BC, Aldrich CC. Bockman MR, et al. Among authors: rhee ky. J Med Chem. 2015 Sep 24;58(18):7349-7369. doi: 10.1021/acs.jmedchem.5b00719. Epub 2015 Sep 3. J Med Chem. 2015. PMID: 26299766 Free PMC article.

2

S-nitroso proteome of Mycobacterium tuberculosis: Enzymes of intermediary metabolism and antioxidant defense.

Rhee KY, Erdjument-Bromage H, Tempst P, Nathan CF. Rhee KY, et al. Proc Natl Acad Sci U S A. 2005 Jan 11;102(2):467-72. doi: 10.1073/pnas.0406133102. Epub 2004 Dec 30. Proc Natl Acad Sci U S A. 2005. PMID: 15626759 Free PMC article.

3

Gluconeogenic carbon flow of tricarboxylic acid cycle intermediates is critical for Mycobacterium tuberculosis to establish and maintain infection.

Marrero J, Rhee KY, Schnappinger D, Pethe K, Ehrt S. Marrero J, et al. Among authors: rhee ky. Proc Natl Acad Sci U S A. 2010 May 25;107(21):9819-24. doi: 10.1073/pnas.1000715107. Epub 2010 May 3. Proc Natl Acad Sci U S A. 2010. PMID: 20439709 Free PMC article.

4

Metabolomics of Mycobacterium tuberculosis reveals compartmentalized co-catabolism of carbon substrates.

de Carvalho LP, Fischer SM, Marrero J, Nathan C, Ehrt S, Rhee KY. de Carvalho LP, et al. Among authors: rhee ky. Chem Biol. 2010 Oct 29;17(10):1122-31. doi: 10.1016/j.chembiol.2010.08.009. Chem Biol. 2010. PMID: 21035735

5

Virulence of Mycobacterium tuberculosis depends on lipoamide dehydrogenase, a member of three multienzyme complexes.

Venugopal A, Bryk R, Shi S, Rhee K, Rath P, Schnappinger D, Ehrt S, Nathan C. Venugopal A, et al. Cell Host Microbe. 2011 Jan 20;9(1):21-31. doi: 10.1016/j.chom.2010.12.004. Cell Host Microbe. 2011. PMID: 21238944 Free PMC article.

6

Depletion of antibiotic targets has widely varying effects on growth.

Wei JR, Krishnamoorthy V, Murphy K, Kim JH, Schnappinger D, Alber T, Sassetti CM, Rhee KY, Rubin EJ. Wei JR, et al. Among authors: rhee ky. Proc Natl Acad Sci U S A. 2011 Mar 8;108(10):4176-81. doi: 10.1073/pnas.1018301108. Epub 2011 Feb 22. Proc Natl Acad Sci U S A. 2011. PMID: 21368134 Free PMC article.

7

Central carbon metabolism in Mycobacterium tuberculosis: an unexpected frontier.

Rhee KY, de Carvalho LP, Bryk R, Ehrt S, Marrero J, Park SW, Schnappinger D, Venugopal A, Nathan C. Rhee KY, et al. Trends Microbiol. 2011 Jul;19(7):307-14. doi: 10.1016/j.tim.2011.03.008. Epub 2011 May 10. Trends Microbiol. 2011. PMID: 21561773 Free PMC article.

8

Evaluating the sensitivity of Mycobacterium tuberculosis to biotin deprivation using regulated gene expression.

Woong Park S, Klotzsche M, Wilson DJ, Boshoff HI, Eoh H, Manjunatha U, Blumenthal A, Rhee K, Barry CE 3rd, Aldrich CC, Ehrt S, Schnappinger D. Woong Park S, et al. PLoS Pathog. 2011 Sep;7(9):e1002264. doi: 10.1371/journal.ppat.1002264. Epub 2011 Sep 29. PLoS Pathog. 2011. PMID: 21980288 Free PMC article.

9

Nitazoxanide Disrupts Membrane Potential and Intrabacterial pH Homeostasis of Mycobacterium tuberculosis.

de Carvalho LP, Darby CM, Rhee KY, Nathan C. de Carvalho LP, et al. Among authors: rhee ky. ACS Med Chem Lett. 2011;2(11):849-854. doi: 10.1021/ml200157f. ACS Med Chem Lett. 2011. PMID: 22096616 Free PMC article.

10

A genetic strategy to identify targets for the development of drugs that prevent bacterial persistence.

Kim JH, O'Brien KM, Sharma R, Boshoff HI, Rehren G, Chakraborty S, Wallach JB, Monteleone M, Wilson DJ, Aldrich CC, Barry CE 3rd, Rhee KY, Ehrt S, Schnappinger D. Kim JH, et al. Among authors: rhee ky. Proc Natl Acad Sci U S A. 2013 Nov 19;110(47):19095-100. doi: 10.1073/pnas.1315860110. Epub 2013 Nov 4. Proc Natl Acad Sci U S A. 2013. PMID: 24191058 Free PMC article.

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