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Association between endometriosis and the interleukin 1A (IL1A) locus.
Sapkota Y, Low SK, Attia J, Gordon SD, Henders AK, Holliday EG, MacGregor S, Martin NG, McEvoy M, Morris AP, Takahashi A, Scott RJ, Kubo M, Zondervan KT, Montgomery GW, Nyholt DR. Sapkota Y, et al. Hum Reprod. 2015 Jan;30(1):239-48. doi: 10.1093/humrep/deu267. Epub 2014 Oct 21. Hum Reprod. 2015. PMID: 25336714 Free PMC article.
Genetic burden associated with varying degrees of disease severity in endometriosis.
Sapkota Y, Attia J, Gordon SD, Henders AK, Holliday EG, Rahmioglu N, MacGregor S, Martin NG, McEvoy M, Morris AP, Scott RJ, Zondervan KT, Montgomery GW, Nyholt DR. Sapkota Y, et al. Mol Hum Reprod. 2015 Jul;21(7):594-602. doi: 10.1093/molehr/gav021. Epub 2015 Apr 16. Mol Hum Reprod. 2015. PMID: 25882541 Free PMC article.
Endometrial vezatin and its association with endometriosis risk.
Holdsworth-Carson SJ, Fung JN, Luong HT, Sapkota Y, Bowdler LM, Wallace L, Teh WT, Powell JE, Girling JE, Healey M, Montgomery GW, Rogers PA. Holdsworth-Carson SJ, et al. Among authors: sapkota y. Hum Reprod. 2016 May;31(5):999-1013. doi: 10.1093/humrep/dew047. Epub 2016 Mar 22. Hum Reprod. 2016. PMID: 27005890
Endometriosis risk alleles at 1p36.12 act through inverse regulation of CDC42 and LINC00339.
Powell JE, Fung JN, Shakhbazov K, Sapkota Y, Cloonan N, Hemani G, Hillman KM, Kaufmann S, Luong HT, Bowdler L, Painter JN, Holdsworth-Carson SJ, Visscher PM, Dinger ME, Healey M, Nyholt DR, French JD, Edwards SL, Rogers PA, Montgomery GW. Powell JE, et al. Among authors: sapkota y. Hum Mol Genet. 2016 Nov 15;25(22):5046-5058. doi: 10.1093/hmg/ddw320. Hum Mol Genet. 2016. PMID: 28171565
The genetic regulation of transcription in human endometrial tissue.
Fung JN, Girling JE, Lukowski SW, Sapkota Y, Wallace L, Holdsworth-Carson SJ, Henders AK, Healey M, Rogers PAW, Powell JE, Montgomery GW. Fung JN, et al. Among authors: sapkota y. Hum Reprod. 2017 Apr 1;32(4):893-904. doi: 10.1093/humrep/dex006. Hum Reprod. 2017. PMID: 28177073
Association Between Telomere Length and Risk of Cancer and Non-Neoplastic Diseases: A Mendelian Randomization Study.
Telomeres Mendelian Randomization Collaboration; Haycock PC, Burgess S, Nounu A, Zheng J, Okoli GN, Bowden J, Wade KH, Timpson NJ, Evans DM, Willeit P, Aviv A, Gaunt TR, Hemani G, Mangino M, Ellis HP, Kurian KM, Pooley KA, Eeles RA, Lee JE, Fang S, Chen WV, Law MH, Bowdler LM, Iles MM, Yang Q, Worrall BB, Markus HS, Hung RJ, Amos CI, Spurdle AB, Thompson DJ, O'Mara TA, Wolpin B, Amundadottir L, Stolzenberg-Solomon R, Trichopoulou A, Onland-Moret NC, Lund E, Duell EJ, Canzian F, Severi G, Overvad K, Gunter MJ, Tumino R, Svenson U, van Rij A, Baas AF, Bown MJ, Samani NJ, van t'Hof FNG, Tromp G, Jones GT, Kuivaniemi H, Elmore JR, Johansson M, Mckay J, Scelo G, Carreras-Torres R, Gaborieau V, Brennan P, Bracci PM, Neale RE, Olson SH, Gallinger S, Li D, Petersen GM, Risch HA, Klein AP, Han J, Abnet CC, Freedman ND, Taylor PR, Maris JM, Aben KK, Kiemeney LA, Vermeulen SH, Wiencke JK, Walsh KM, Wrensch M, Rice T, Turnbull C, Litchfield K, Paternoster L, Standl M, Abecasis GR, SanGiovanni JP, Li Y, Mijatovic V, Sapkota Y, Low SK, Zondervan KT, Montgomery GW, Nyholt DR, van Heel DA, Hunt K, Arking DE, Ashar FN, Sotoodehnia N, Woo D, Rosand J, Comeau ME, Brown WM, Silverman EK, Hokan… See abstract for full author list ➔ Telomeres Mendelian Randomization Collaboration, et al. Among authors: sapkota y. JAMA Oncol. 2017 May 1;3(5):636-651. doi: 10.1001/jamaoncol.2016.5945. JAMA Oncol. 2017. PMID: 28241208 Free PMC article.
Meta-analysis identifies five novel loci associated with endometriosis highlighting key genes involved in hormone metabolism.
Sapkota Y, Steinthorsdottir V, Morris AP, Fassbender A, Rahmioglu N, De Vivo I, Buring JE, Zhang F, Edwards TL, Jones S, O D, Peterse D, Rexrode KM, Ridker PM, Schork AJ, MacGregor S, Martin NG, Becker CM, Adachi S, Yoshihara K, Enomoto T, Takahashi A, Kamatani Y, Matsuda K, Kubo M, Thorleifsson G, Geirsson RT, Thorsteinsdottir U, Wallace LM; iPSYCH-SSI-Broad Group; Yang J, Velez Edwards DR, Nyegaard M, Low SK, Zondervan KT, Missmer SA, D'Hooghe T, Montgomery GW, Chasman DI, Stefansson K, Tung JY, Nyholt DR. Sapkota Y, et al. Nat Commun. 2017 May 24;8:15539. doi: 10.1038/ncomms15539. Nat Commun. 2017. PMID: 28537267 Free PMC article.
Analysis of potential protein-modifying variants in 9000 endometriosis patients and 150000 controls of European ancestry.
Sapkota Y, Vivo I, Steinthorsdottir V, Fassbender A, Bowdler L, Buring JE, Edwards TL, Jones S, O D, Peterse D, Rexrode KM, Ridker PM, Schork AJ, Thorleifsson G, Wallace LM; iPSYCH-SSI-Broad Group; Kraft P, Morris AP, Nyholt DR, Edwards DRV, Nyegaard M, D'Hooghe T, Chasman DI, Stefansson K, Missmer SA, Montgomery GW. Sapkota Y, et al. Sci Rep. 2017 Sep 12;7(1):11380. doi: 10.1038/s41598-017-10440-9. Sci Rep. 2017. PMID: 28900119 Free PMC article.
130 results