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Page 1
Ferroquine and artesunate in African adults and children with Plasmodium falciparum malaria: a phase 2, multicentre, randomised, double-blind, dose-ranging, non-inferiority study.
Held J, Supan C, Salazar CL, Tinto H, Bonkian LN, Nahum A, Moulero B, Sié A, Coulibaly B, Sirima SB, Siribie M, Otsyula N, Otieno L, Abdallah AM, Kimutai R, Bouyou-Akotet M, Kombila M, Koiwai K, Cantalloube C, Din-Bell C, Djeriou E, Waitumbi J, Mordmüller B, Ter-Minassian D, Lell B, Kremsner PG. Held J, et al. Among authors: supan c. Lancet Infect Dis. 2015 Dec;15(12):1409-19. doi: 10.1016/S1473-3099(15)00079-1. Epub 2015 Sep 3. Lancet Infect Dis. 2015. PMID: 26342427 Clinical Trial.
Phase I randomized dose-ascending placebo-controlled trials of ferroquine--a candidate anti-malarial drug--in adults with asymptomatic Plasmodium falciparum infection.
Mombo-Ngoma G, Supan C, Dal-Bianco MP, Missinou MA, Matsiegui PB, Ospina Salazar CL, Issifou S, Ter-Minassian D, Ramharter M, Kombila M, Kremsner PG, Lell B. Mombo-Ngoma G, et al. Among authors: supan c. Malar J. 2011 Mar 1;10:53. doi: 10.1186/1475-2875-10-53. Malar J. 2011. PMID: 21362162 Free PMC article. Clinical Trial.
Sporozoite Route of Infection Influences In Vitro var Gene Transcription of Plasmodium falciparum Parasites From Controlled Human Infections.
Dimonte S, Bruske EI, Hass J, Supan C, Salazar CL, Held J, Tschan S, Esen M, Flötenmeyer M, Koch I, Berger J, Bachmann A, Sim BK, Hoffman SL, Kremsner PG, Mordmüller B, Frank M. Dimonte S, et al. Among authors: supan c. J Infect Dis. 2016 Sep 15;214(6):884-94. doi: 10.1093/infdis/jiw225. Epub 2016 Jun 7. J Infect Dis. 2016. PMID: 27279526 Free PMC article.
Safety and efficacy of the choline analogue SAR97276 for malaria treatment: results of two phase 2, open-label, multicenter trials in African patients.
Held J, Supan C, Salazar CLO, Tinto H, Bonkian LN, Nahum A, Sié A, Abdulla S, Cantalloube C, Djeriou E, Bouyou-Akotet M, Ogutu B, Mordmüller B, Kreidenweiss A, Siribie M, Sirima SB, Kremsner PG. Held J, et al. Among authors: supan c. Malar J. 2017 May 4;16(1):188. doi: 10.1186/s12936-017-1832-x. Malar J. 2017. PMID: 28472957 Free PMC article. Clinical Trial.
Phase 2a, Open-Label, 4-Escalating-Dose, Randomized Multicenter Study Evaluating the Safety and Activity of Ferroquine (SSR97193) Plus Artesunate, versus Amodiaquine Plus Artesunate, in African Adult Men with Uncomplicated Plasmodium falciparum Malaria.
Supan C, Mombo-Ngoma G, Kombila M, Ospina Salazar CL, Held J, Lell B, Cantalloube C, Djeriou E, Ogutu B, Waitumbi J, Otsula N, Apollo D, Polhemus ME, Kremsner PG, Walsh DS. Supan C, et al. Am J Trop Med Hyg. 2017 Aug;97(2):514-525. doi: 10.4269/ajtmh.16-0731. Epub 2017 Jul 19. Am J Trop Med Hyg. 2017. PMID: 28722611 Free PMC article. Clinical Trial.
Intermittent preventive treatment against malaria in infants in Gabon--a randomized, double-blind, placebo-controlled trial.
Grobusch MP, Lell B, Schwarz NG, Gabor J, Dornemann J, Potschke M, Oyakhirome S, Kiessling GC, Necek M, Langin MU, Klein Klouwenberg P, Klopfer A, Naumann B, Altun H, Agnandji ST, Goesch J, Decker M, Salazar CL, Supan C, Kombila DU, Borchert L, Koster KB, Pongratz P, Adegnika AA, Glasenapp Iv, Issifou S, Kremsner PG. Grobusch MP, et al. Among authors: supan c. J Infect Dis. 2007 Dec 1;196(11):1595-602. doi: 10.1086/522160. Epub 2007 Oct 25. J Infect Dis. 2007. PMID: 18008242 Clinical Trial.
A thirteen-year analysis of Plasmodium falciparum populations reveals high conservation of the mutant pfcrt haplotype despite the withdrawal of chloroquine from national treatment guidelines in Gabon.
Frank M, Lehners N, Mayengue PI, Gabor J, Dal-Bianco M, Kombila DU, Ngoma GM, Supan C, Lell B, Ntoumi F, Grobusch MP, Dietz K, Kremsner PG. Frank M, et al. Among authors: supan c. Malar J. 2011 Oct 17;10:304. doi: 10.1186/1475-2875-10-304. Malar J. 2011. PMID: 22004584 Free PMC article.
Direct venous inoculation of Plasmodium falciparum sporozoites for controlled human malaria infection: a dose-finding trial in two centres.
Mordmüller B, Supan C, Sim KL, Gómez-Pérez GP, Ospina Salazar CL, Held J, Bolte S, Esen M, Tschan S, Joanny F, Lamsfus Calle C, Löhr SJ, Lalremruata A, Gunasekera A, James ER, Billingsley PF, Richman A, Chakravarty S, Legarda A, Muñoz J, Antonijoan RM, Ballester MR, Hoffman SL, Alonso PL, Kremsner PG. Mordmüller B, et al. Among authors: supan c. Malar J. 2015 Mar 18;14:117. doi: 10.1186/s12936-015-0628-0. Malar J. 2015. PMID: 25889522 Free PMC article. Clinical Trial.