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RIPK1 ensures intestinal homeostasis by protecting the epithelium against apoptosis.
Takahashi N, Vereecke L, Bertrand MJ, Duprez L, Berger SB, Divert T, Gonçalves A, Sze M, Gilbert B, Kourula S, Goossens V, Lefebvre S, Günther C, Becker C, Bertin J, Gough PJ, Declercq W, van Loo G, Vandenabeele P. Takahashi N, et al. Among authors: divert t. Nature. 2014 Sep 4;513(7516):95-9. doi: 10.1038/nature13706. Nature. 2014. PMID: 25186904
Tozasertib Analogues as Inhibitors of Necroptotic Cell Death.
Hofmans S, Devisscher L, Martens S, Van Rompaey D, Goossens K, Divert T, Nerinckx W, Takahashi N, De Winter H, Van Der Veken P, Goossens V, Vandenabeele P, Augustyns K. Hofmans S, et al. Among authors: divert t. J Med Chem. 2018 Mar 8;61(5):1895-1920. doi: 10.1021/acs.jmedchem.7b01449. Epub 2018 Feb 20. J Med Chem. 2018. PMID: 29437386
Reduced protection of RIPK3-deficient mice against influenza by matrix protein 2 ectodomain targeted active and passive vaccination strategies.
Oltean T, Ibanez LI, Divert T, Ysenbaert T, Van Eeckhoutte H, Goossens V, Schotsaert M, Bracke K, Schepens B, Maelfait J, Takahashi N, Saelens X, Vandenabeele P. Oltean T, et al. Among authors: divert t. Cell Death Dis. 2022 Mar 29;13(3):280. doi: 10.1038/s41419-022-04710-2. Cell Death Dis. 2022. PMID: 35351865 Free PMC article.
Executioner caspases 3 and 7 are dispensable for intestinal epithelium turnover and homeostasis at steady state.
Ghazavi F, Huysentruyt J, De Coninck J, Kourula S, Martens S, Hassannia B, Wartewig T, Divert T, Roelandt R, Popper B, Hiergeist A, Tougaard P, Vanden Berghe T, Joossens M, Berx G, Takahashi N, Wahida A, Vandenabeele P. Ghazavi F, et al. Among authors: divert t. Proc Natl Acad Sci U S A. 2022 Feb 8;119(6):e2024508119. doi: 10.1073/pnas.2024508119. Proc Natl Acad Sci U S A. 2022. PMID: 35105800 Free PMC article.
Passenger Mutations Confound Interpretation of All Genetically Modified Congenic Mice.
Vanden Berghe T, Hulpiau P, Martens L, Vandenbroucke RE, Van Wonterghem E, Perry SW, Bruggeman I, Divert T, Choi SM, Vuylsteke M, Shestopalov VI, Libert C, Vandenabeele P. Vanden Berghe T, et al. Among authors: divert t. Immunity. 2015 Jul 21;43(1):200-9. doi: 10.1016/j.immuni.2015.06.011. Epub 2015 Jul 7. Immunity. 2015. PMID: 26163370 Free PMC article.
RIPK1 protects naive and regulatory T cells from TNFR1-induced apoptosis.
Huysentruyt J, Steels W, Ruiz Perez M, Verstraeten B, Vadi M, Divert T, Flies K, Takahashi N, Lambrecht BN, Declercq W, Vanden Berghe T, Maelfait J, Vandenabeele P, Tougaard P. Huysentruyt J, et al. Among authors: divert t. Cell Death Differ. 2024 May 11. doi: 10.1038/s41418-024-01301-w. Online ahead of print. Cell Death Differ. 2024. PMID: 38734851
Type 1 immunity enables neonatal thymic ILC1 production.
Tougaard P, Pérez MR, Steels W, Huysentruyt J, Verstraeten B, Vetters J, Divert T, Gonçalves A, Roelandt R, Takahashi N, Janssens S, Buus TB, Taghon T, Leclercq G, Vandenabeele P. Tougaard P, et al. Among authors: divert t. Sci Adv. 2024 Jan 19;10(3):eadh5520. doi: 10.1126/sciadv.adh5520. Epub 2024 Jan 17. Sci Adv. 2024. PMID: 38232171 Free PMC article.