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The E3 ligase RNF43 inhibits Wnt signaling downstream of mutated β-catenin by sequestering TCF4 to the nuclear membrane.
Loregger A, Grandl M, Mejías-Luque R, Allgäuer M, Degenhart K, Haselmann V, Oikonomou C, Hatzis P, Janssen KP, Nitsche U, Gradl D, van den Broek O, Destree O, Ulm K, Neumaier M, Kalali B, Jung A, Varela I, Schmid RM, Rad R, Busch DH, Gerhard M. Loregger A, et al. Among authors: busch dh. Sci Signal. 2015 Sep 8;8(393):ra90. doi: 10.1126/scisignal.aac6757. Sci Signal. 2015. PMID: 26350900
A novel line immunoassay based on recombinant virulence factors enables highly specific and sensitive serologic diagnosis of Helicobacter pylori infection.
Formichella L, Romberg L, Bolz C, Vieth M, Geppert M, Göttner G, Nölting C, Walter D, Schepp W, Schneider A, Ulm K, Wolf P, Busch DH, Soutschek E, Gerhard M. Formichella L, et al. Among authors: busch dh. Clin Vaccine Immunol. 2013 Nov;20(11):1703-10. doi: 10.1128/CVI.00433-13. Epub 2013 Sep 4. Clin Vaccine Immunol. 2013. PMID: 24006137 Free PMC article.
T cell-specific inactivation of mouse CD2 by CRISPR/Cas9.
Beil-Wagner J, Dössinger G, Schober K, vom Berg J, Tresch A, Grandl M, Palle P, Mair F, Gerhard M, Becher B, Busch DH, Buch T. Beil-Wagner J, et al. Among authors: busch dh. Sci Rep. 2016 Feb 23;6:21377. doi: 10.1038/srep21377. Sci Rep. 2016. PMID: 26903281 Free PMC article.
Helicobacter pylori adhesin HopQ engages in a virulence-enhancing interaction with human CEACAMs.
Javaheri A, Kruse T, Moonens K, Mejías-Luque R, Debraekeleer A, Asche CI, Tegtmeyer N, Kalali B, Bach NC, Sieber SA, Hill DJ, Königer V, Hauck CR, Moskalenko R, Haas R, Busch DH, Klaile E, Slevogt H, Schmidt A, Backert S, Remaut H, Singer BB, Gerhard M. Javaheri A, et al. Among authors: busch dh. Nat Microbiol. 2016 Oct 17;2:16189. doi: 10.1038/nmicrobiol.2016.189. Nat Microbiol. 2016. PMID: 27748768
Gut Microbiota-Derived Propionate Regulates the Expression of Reg3 Mucosal Lectins and Ameliorates Experimental Colitis in Mice.
Bajic D, Niemann A, Hillmer AK, Mejias-Luque R, Bluemel S, Docampo M, Funk MC, Tonin E, Boutros M, Schnabl B, Busch DH, Miki T, Schmid RM, van den Brink MRM, Gerhard M, Stein-Thoeringer CK. Bajic D, et al. Among authors: busch dh. J Crohns Colitis. 2020 Oct 5;14(10):1462-1472. doi: 10.1093/ecco-jcc/jjaa065. J Crohns Colitis. 2020. PMID: 32227170 Free PMC article.
Recruitment of highly cytotoxic CD8+ T cell receptors in mild SARS-CoV-2 infection.
Wagner KI, Mateyka LM, Jarosch S, Grass V, Weber S, Schober K, Hammel M, Burrell T, Kalali B, Poppert H, Beyer H, Schambeck S, Holdenrieder S, Strötges-Achatz A, Haselmann V, Neumaier M, Erber J, Priller A, Yazici S, Roggendorf H, Odendahl M, Tonn T, Dick A, Witter K, Mijočević H, Protzer U, Knolle PA, Pichlmair A, Crowell CS, Gerhard M, D'Ippolito E, Busch DH. Wagner KI, et al. Among authors: busch dh. Cell Rep. 2022 Jan 11;38(2):110214. doi: 10.1016/j.celrep.2021.110214. Epub 2021 Dec 17. Cell Rep. 2022. PMID: 34968416 Free PMC article.
CagA-specific Gastric CD8+ Tissue-Resident T Cells Control Helicobacter pylori During the Early Infection Phase.
Koch MRA, Gong R, Friedrich V, Engelsberger V, Kretschmer L, Wanisch A, Jarosch S, Ralser A, Lugen B, Quante M, Vieth M, Vasapolli R, Schulz C, Buchholz VR, Busch DH, Mejías-Luque R, Gerhard M. Koch MRA, et al. Among authors: busch dh. Gastroenterology. 2023 Apr;164(4):550-566. doi: 10.1053/j.gastro.2022.12.016. Epub 2022 Dec 30. Gastroenterology. 2023. PMID: 36587707
NF-kappaB is a negative regulator of IL-1beta secretion as revealed by genetic and pharmacological inhibition of IKKbeta.
Greten FR, Arkan MC, Bollrath J, Hsu LC, Goode J, Miething C, Göktuna SI, Neuenhahn M, Fierer J, Paxian S, Van Rooijen N, Xu Y, O'Cain T, Jaffee BB, Busch DH, Duyster J, Schmid RM, Eckmann L, Karin M. Greten FR, et al. Among authors: busch dh. Cell. 2007 Sep 7;130(5):918-31. doi: 10.1016/j.cell.2007.07.009. Cell. 2007. PMID: 17803913 Free PMC article.
362 results