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The E3 ligase RNF43 inhibits Wnt signaling downstream of mutated β-catenin by sequestering TCF4 to the nuclear membrane.
Loregger A, Grandl M, Mejías-Luque R, Allgäuer M, Degenhart K, Haselmann V, Oikonomou C, Hatzis P, Janssen KP, Nitsche U, Gradl D, van den Broek O, Destree O, Ulm K, Neumaier M, Kalali B, Jung A, Varela I, Schmid RM, Rad R, Busch DH, Gerhard M. Loregger A, et al. Among authors: gerhard m. Sci Signal. 2015 Sep 8;8(393):ra90. doi: 10.1126/scisignal.aac6757. Sci Signal. 2015. PMID: 26350900
Pathogenesis of Helicobacter pylori infection.
Gerhard M, Rad R, Prinz C, Naumann M. Gerhard M, et al. Helicobacter. 2002;7 Suppl 1:17-23. doi: 10.1046/j.1523-5378.7.s1.3.x. Helicobacter. 2002. PMID: 12197905 Review.
Lack of RUNX3 regulation in human gastric cancer.
Friedrich MJ, Rad R, Langer R, Voland P, Hoefler H, Schmid RM, Prinz C, Gerhard M. Friedrich MJ, et al. Among authors: gerhard m. J Pathol. 2006 Oct;210(2):141-6. doi: 10.1002/path.2042. J Pathol. 2006. PMID: 16917803
ITF-2 is disrupted via allelic loss of chromosome 18q21, and ITF-2B expression is lost at the adenoma-carcinoma transition.
Herbst A, Bommer GT, Kriegl L, Jung A, Behrens A, Csanadi E, Gerhard M, Bolz C, Riesenberg R, Zimmermann W, Dietmaier W, Wolf I, Brabletz T, Göke B, Kolligs FT. Herbst A, et al. Among authors: gerhard m. Gastroenterology. 2009 Aug;137(2):639-48, 648.e1-9. doi: 10.1053/j.gastro.2009.04.049. Epub 2009 Apr 23. Gastroenterology. 2009. PMID: 19394332
184 results