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Mutant p53(R175H) upregulates Twist1 expression and promotes epithelial-mesenchymal transition in immortalized prostate cells.
Kogan-Sakin I, Tabach Y, Buganim Y, Molchadsky A, Solomon H, Madar S, Kamer I, Stambolsky P, Shelly A, Goldfinger N, Valsesia-Wittmann S, Puisieux A, Zundelevich A, Gal-Yam EN, Avivi C, Barshack I, Brait M, Sidransky D, Domany E, Rotter V. Kogan-Sakin I, et al. Among authors: molchadsky a. Cell Death Differ. 2011 Feb;18(2):271-81. doi: 10.1038/cdd.2010.94. Epub 2010 Aug 6. Cell Death Differ. 2011. PMID: 20689556 Free PMC article.
p53 counteracts reprogramming by inhibiting mesenchymal-to-epithelial transition.
Brosh R, Assia-Alroy Y, Molchadsky A, Bornstein C, Dekel E, Madar S, Shetzer Y, Rivlin N, Goldfinger N, Sarig R, Rotter V. Brosh R, et al. Among authors: molchadsky a. Cell Death Differ. 2013 Feb;20(2):312-20. doi: 10.1038/cdd.2012.125. Epub 2012 Sep 21. Cell Death Differ. 2013. PMID: 22996684 Free PMC article.
The onset of p53 loss of heterozygosity is differentially induced in various stem cell types and may involve the loss of either allele.
Shetzer Y, Kagan S, Koifman G, Sarig R, Kogan-Sakin I, Charni M, Kaufman T, Zapatka M, Molchadsky A, Rivlin N, Dinowitz N, Levin S, Landan G, Goldstein I, Goldfinger N, Pe'er D, Radlwimmer B, Lichter P, Rotter V, Aloni-Grinstein R. Shetzer Y, et al. Among authors: molchadsky a. Cell Death Differ. 2014 Sep;21(9):1419-31. doi: 10.1038/cdd.2014.57. Epub 2014 May 16. Cell Death Differ. 2014. PMID: 24832469 Free PMC article.
p53, a novel regulator of lipid metabolism pathways.
Goldstein I, Ezra O, Rivlin N, Molchadsky A, Madar S, Goldfinger N, Rotter V. Goldstein I, et al. Among authors: molchadsky a. J Hepatol. 2012 Mar;56(3):656-62. doi: 10.1016/j.jhep.2011.08.022. Epub 2011 Oct 26. J Hepatol. 2012. PMID: 22037227 Free article.
p53 in liver pathologies-taking the good with the bad.
Charni M, Rivlin N, Molchadsky A, Aloni-Grinstein R, Rotter V. Charni M, et al. Among authors: molchadsky a. J Mol Med (Berl). 2014 Dec;92(12):1229-34. doi: 10.1007/s00109-014-1223-5. Epub 2014 Nov 19. J Mol Med (Berl). 2014. PMID: 25404244 Review.
p53 on the crossroad between regeneration and cancer.
Charni M, Aloni-Grinstein R, Molchadsky A, Rotter V. Charni M, et al. Among authors: molchadsky a. Cell Death Differ. 2017 Jan;24(1):8-14. doi: 10.1038/cdd.2016.117. Epub 2016 Oct 21. Cell Death Differ. 2017. PMID: 27768121 Free PMC article. Review.
26 results