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Perhexiline activates KLF14 and reduces atherosclerosis by modulating ApoA-I production.
Guo Y, Fan Y, Zhang J, Lomberk GA, Zhou Z, Sun L, Mathison AJ, Garcia-Barrio MT, Zhang J, Zeng L, Li L, Pennathur S, Willer CJ, Rader DJ, Urrutia R, Chen YE. Guo Y, et al. Among authors: lomberk ga. J Clin Invest. 2015 Oct 1;125(10):3819-30. doi: 10.1172/JCI79048. Epub 2015 Sep 14. J Clin Invest. 2015. PMID: 26368306 Free PMC article.
Detailed structural-functional analysis of the Krüppel-like factor 16 (KLF16) transcription factor reveals novel mechanisms for silencing Sp/KLF sites involved in metabolism and endocrinology.
Daftary GS, Lomberk GA, Buttar NS, Allen TW, Grzenda A, Zhang J, Zheng Y, Mathison AJ, Gada RP, Calvo E, Iovanna JL, Billadeau DD, Prendergast FG, Urrutia R. Daftary GS, et al. Among authors: lomberk ga. J Biol Chem. 2012 Mar 2;287(10):7010-25. doi: 10.1074/jbc.M111.266007. Epub 2011 Dec 27. J Biol Chem. 2012. PMID: 22203677 Free PMC article.
Membrane-to-nucleus signaling links insulin-like growth factor-1- and stem cell factor-activated pathways.
Hayashi Y, Asuzu DT, Gibbons SJ, Aarsvold KH, Bardsley MR, Lomberk GA, Mathison AJ, Kendrick ML, Shen KR, Taguchi T, Gupta A, Rubin BP, Fletcher JA, Farrugia G, Urrutia RA, Ordog T. Hayashi Y, et al. Among authors: lomberk ga. PLoS One. 2013 Oct 7;8(10):e76822. doi: 10.1371/journal.pone.0076822. eCollection 2013. PLoS One. 2013. PMID: 24116170 Free PMC article.
Functional validation reveals the novel missense V419L variant in TGFBR2 associated with Loeys-Dietz syndrome (LDS) impairs canonical TGF-β signaling.
Cousin MA, Zimmermann MT, Mathison AJ, Blackburn PR, Boczek NJ, Oliver GR, Lomberk GA, Urrutia RA, Deyle DR, Klee EW. Cousin MA, et al. Among authors: lomberk ga. Cold Spring Harb Mol Case Stud. 2017 Jul 5;3(4):a001727. doi: 10.1101/mcs.a001727. Print 2017 Jul. Cold Spring Harb Mol Case Stud. 2017. PMID: 28679693 Free PMC article.
Aurora kinase B-phosphorylated HP1α functions in chromosomal instability.
Williams MM, Mathison AJ, Christensen T, Greipp PT, Knutson DL, Klee EW, Zimmermann MT, Iovanna J, Lomberk GA, Urrutia RA. Williams MM, et al. Among authors: lomberk ga. Cell Cycle. 2019 Jun;18(12):1407-1421. doi: 10.1080/15384101.2019.1618126. Epub 2019 May 26. Cell Cycle. 2019. PMID: 31130069 Free PMC article.
31 results