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Multicentre double-blind randomized controlled trial of perhexiline as a metabolic modulator to augment myocardial protection in patients with left ventricular hypertrophy undergoing cardiac surgery.
Senanayake EL, Howell NJ, Ranasinghe AM, Drury NE, Freemantle N, Frenneaux M, Oelofse T, Green D, Wilson IC, Rooney SJ, Mascaro J, Graham TR, Bhudia S, Lewis M, Pagano D. Senanayake EL, et al. Eur J Cardiothorac Surg. 2015 Sep;48(3):354-62. doi: 10.1093/ejcts/ezu452. Epub 2014 Dec 23. Eur J Cardiothorac Surg. 2015. PMID: 25538197 Clinical Trial.
Perhexiline.
Ashrafian H, Horowitz JD, Frenneaux MP. Ashrafian H, et al. Among authors: frenneaux mp. Cardiovasc Drug Rev. 2007 Spring;25(1):76-97. doi: 10.1111/j.1527-3466.2007.00006.x. Cardiovasc Drug Rev. 2007. PMID: 17445089 Review.
The effect of perhexiline on myocardial protection during coronary artery surgery: a two-centre, randomized, double-blind, placebo-controlled trial.
Drury NE, Howell NJ, Calvert MJ, Weber RJ, Senanayake EL, Lewis ME, Hyde JA, Green DH, Mascaro JG, Wilson IC, Graham TR, Rooney SJ, Viant MR, Freemantle N, Frenneaux MP, Pagano D; investigators. Drury NE, et al. Among authors: frenneaux mp. Eur J Cardiothorac Surg. 2015 Mar;47(3):464-72. doi: 10.1093/ejcts/ezu238. Epub 2014 Jun 19. Eur J Cardiothorac Surg. 2015. PMID: 24948413 Free PMC article. Clinical Trial.
Role of aldehyde dehydrogenase in hypoxic vasodilator effects of nitrite in rats and humans.
Arif S, Borgognone A, Lin EL, O'Sullivan AG, Sharma V, Drury NE, Menon A, Nightingale P, Mascaro J, Bonser RS, Horowitz JD, Feelisch M, Frenneaux MP, Madhani M. Arif S, et al. Among authors: frenneaux mp. Br J Pharmacol. 2015 Jul;172(13):3341-52. doi: 10.1111/bph.13122. Epub 2015 Apr 29. Br J Pharmacol. 2015. PMID: 25754766 Free PMC article.
Does cardiac resynchronization therapy restore peripheral circulatory homeostasis?
Ajaero CN, Chong CR, Procter NEK, Liu S, Chirkov YY, Heresztyn T, Chan WPA, Arstall MA, McGavigan AD, Frenneaux MP, Horowitz JD. Ajaero CN, et al. Among authors: frenneaux mp. ESC Heart Fail. 2018 Feb;5(1):129-138. doi: 10.1002/ehf2.12211. Epub 2017 Oct 13. ESC Heart Fail. 2018. PMID: 29030923 Free PMC article.
296 results