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Parkinson's disease: From human genetics to clinical trials.
van der Brug MP, Singleton A, Gasser T, Lewis PA. van der Brug MP, et al. Among authors: lewis pa. Sci Transl Med. 2015 Sep 16;7(305):205ps20. doi: 10.1126/scitranslmed.aaa8280. Sci Transl Med. 2015. PMID: 26378242 Free PMC article.
Pathogenic LRRK2 mutations do not alter gene expression in cell model systems or human brain tissue.
Devine MJ, Kaganovich A, Ryten M, Mamais A, Trabzuni D, Manzoni C, McGoldrick P, Chan D, Dillman A, Zerle J, Horan S, Taanman JW, Hardy J, Marti-Masso JF, Healy D, Schapira AH, Wolozin B, Bandopadhyay R, Cookson MR, van der Brug MP, Lewis PA. Devine MJ, et al. Among authors: lewis pa. PLoS One. 2011;6(7):e22489. doi: 10.1371/journal.pone.0022489. Epub 2011 Jul 22. PLoS One. 2011. PMID: 21799870 Free PMC article.
Gene expression in the Parkinson's disease brain.
Lewis PA, Cookson MR. Lewis PA, et al. Brain Res Bull. 2012 Jul 1;88(4):302-12. doi: 10.1016/j.brainresbull.2011.11.016. Epub 2011 Dec 3. Brain Res Bull. 2012. PMID: 22173063 Free PMC article. Review.
LRRK2: cause, risk, and mechanism.
Paisán-Ruiz C, Lewis PA, Singleton AB. Paisán-Ruiz C, et al. Among authors: lewis pa. J Parkinsons Dis. 2013;3(2):85-103. doi: 10.3233/JPD-130192. J Parkinsons Dis. 2013. PMID: 23938341 Free PMC article. Review.
Fine-mapping, gene expression and splicing analysis of the disease associated LRRK2 locus.
Trabzuni D, Ryten M, Emmett W, Ramasamy A, Lackner KJ, Zeller T, Walker R, Smith C, Lewis PA, Mamais A, de Silva R, Vandrovcova J; International Parkinson Disease Genomics Consortium (IPDGC); Hernandez D, Nalls MA, Sharma M, Garnier S, Lesage S, Simon-Sanchez J, Gasser T, Heutink P, Brice A, Singleton A, Cai H, Schadt E, Wood NW, Bandopadhyay R, Weale ME, Hardy J, Plagnol V. Trabzuni D, et al. Among authors: lewis pa. PLoS One. 2013 Aug 13;8(8):e70724. doi: 10.1371/journal.pone.0070724. eCollection 2013. PLoS One. 2013. PMID: 23967090 Free PMC article.
366 results