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SPG7 Is an Essential and Conserved Component of the Mitochondrial Permeability Transition Pore.
Shanmughapriya S, Rajan S, Hoffman NE, Higgins AM, Tomar D, Nemani N, Hines KJ, Smith DJ, Eguchi A, Vallem S, Shaikh F, Cheung M, Leonard NJ, Stolakis RS, Wolfers MP, Ibetti J, Chuprun JK, Jog NR, Houser SR, Koch WJ, Elrod JW, Madesh M. Shanmughapriya S, et al. Among authors: tomar d. Mol Cell. 2015 Oct 1;60(1):47-62. doi: 10.1016/j.molcel.2015.08.009. Epub 2015 Sep 17. Mol Cell. 2015. PMID: 26387735 Free PMC article.
BAG3 regulates contractility and Ca(2+) homeostasis in adult mouse ventricular myocytes.
Feldman AM, Gordon J, Wang J, Song J, Zhang XQ, Myers VD, Tilley DG, Gao E, Hoffman NE, Tomar D, Madesh M, Rabinowitz J, Koch WJ, Su F, Khalili K, Cheung JY. Feldman AM, et al. Among authors: tomar d. J Mol Cell Cardiol. 2016 Mar;92:10-20. doi: 10.1016/j.yjmcc.2016.01.015. Epub 2016 Jan 19. J Mol Cell Cardiol. 2016. PMID: 26796036 Free PMC article.
MCUR1 Is a Scaffold Factor for the MCU Complex Function and Promotes Mitochondrial Bioenergetics.
Tomar D, Dong Z, Shanmughapriya S, Koch DA, Thomas T, Hoffman NE, Timbalia SA, Goldman SJ, Breves SL, Corbally DP, Nemani N, Fairweather JP, Cutri AR, Zhang X, Song J, Jaña F, Huang J, Barrero C, Rabinowitz JE, Luongo TS, Schumacher SM, Rockman ME, Dietrich A, Merali S, Caplan J, Stathopulos P, Ahima RS, Cheung JY, Houser SR, Koch WJ, Patel V, Gohil VM, Elrod JW, Rajan S, Madesh M. Tomar D, et al. Cell Rep. 2016 May 24;15(8):1673-85. doi: 10.1016/j.celrep.2016.04.050. Epub 2016 May 12. Cell Rep. 2016. PMID: 27184846 Free PMC article.
Mitochondrial Ca2+ Uniporter Is a Mitochondrial Luminal Redox Sensor that Augments MCU Channel Activity.
Dong Z, Shanmughapriya S, Tomar D, Siddiqui N, Lynch S, Nemani N, Breves SL, Zhang X, Tripathi A, Palaniappan P, Riitano MF, Worth AM, Seelam A, Carvalho E, Subbiah R, Jaña F, Soboloff J, Peng Y, Cheung JY, Joseph SK, Caplan J, Rajan S, Stathopulos PB, Madesh M. Dong Z, et al. Among authors: tomar d. Mol Cell. 2017 Mar 16;65(6):1014-1028.e7. doi: 10.1016/j.molcel.2017.01.032. Epub 2017 Mar 2. Mol Cell. 2017. PMID: 28262504 Free PMC article.
Platelet microparticles infiltrating solid tumors transfer miRNAs that suppress tumor growth.
Michael JV, Wurtzel JGT, Mao GF, Rao AK, Kolpakov MA, Sabri A, Hoffman NE, Rajan S, Tomar D, Madesh M, Nieman MT, Yu J, Edelstein LC, Rowley JW, Weyrich AS, Goldfinger LE. Michael JV, et al. Among authors: tomar d. Blood. 2017 Aug 3;130(5):567-580. doi: 10.1182/blood-2016-11-751099. Epub 2017 May 12. Blood. 2017. PMID: 28500171 Free PMC article.
Inhibition of NADPH oxidase 2 (NOX2) prevents sepsis-induced cardiomyopathy by improving calcium handling and mitochondrial function.
Joseph LC, Kokkinaki D, Valenti MC, Kim GJ, Barca E, Tomar D, Hoffman NE, Subramanyam P, Colecraft HM, Hirano M, Ratner AJ, Madesh M, Drosatos K, Morrow JP. Joseph LC, et al. Among authors: tomar d. JCI Insight. 2017 Sep 7;2(17):e94248. doi: 10.1172/jci.insight.94248. eCollection 2017 Sep 7. JCI Insight. 2017. PMID: 28878116 Free PMC article.
Haplo-insufficiency of Bcl2-associated athanogene 3 in mice results in progressive left ventricular dysfunction, β-adrenergic insensitivity, and increased apoptosis.
Myers VD, Tomar D, Madesh M, Wang J, Song J, Zhang XQ, Gupta MK, Tahrir FG, Gordon J, McClung JM, Kontos CD, Khalili K, Cheung JY, Feldman AM. Myers VD, et al. Among authors: tomar d. J Cell Physiol. 2018 Sep;233(9):6319-6326. doi: 10.1002/jcp.26482. Epub 2018 Mar 30. J Cell Physiol. 2018. PMID: 29323723 Free PMC article.
Methylene blue counteracts cyanide cardiotoxicity: cellular mechanisms.
Cheung JY, Wang J, Zhang XQ, Song J, Tomar D, Madesh M, Judenherc-Haouzi A, Haouzi P. Cheung JY, et al. Among authors: tomar d. J Appl Physiol (1985). 2018 May 1;124(5):1164-1176. doi: 10.1152/japplphysiol.00967.2017. Epub 2018 Feb 8. J Appl Physiol (1985). 2018. PMID: 29420146 Free PMC article.
MIRO-1 Determines Mitochondrial Shape Transition upon GPCR Activation and Ca2+ Stress.
Nemani N, Carvalho E, Tomar D, Dong Z, Ketschek A, Breves SL, Jaña F, Worth AM, Heffler J, Palaniappan P, Tripathi A, Subbiah R, Riitano MF, Seelam A, Manfred T, Itoh K, Meng S, Sesaki H, Craigen WJ, Rajan S, Shanmughapriya S, Caplan J, Prosser BL, Gill DL, Stathopulos PB, Gallo G, Chan DC, Mishra P, Madesh M. Nemani N, et al. Among authors: tomar d. Cell Rep. 2018 Apr 24;23(4):1005-1019. doi: 10.1016/j.celrep.2018.03.098. Cell Rep. 2018. PMID: 29694881 Free PMC article.
160 results