Rathmell JC - Search Results

1

MYC Disrupts the Circadian Clock and Metabolism in Cancer Cells.

Altman BJ, Hsieh AL, Sengupta A, Krishnanaiah SY, Stine ZE, Walton ZE, Gouw AM, Venkataraman A, Li B, Goraksha-Hicks P, Diskin SJ, Bellovin DI, Simon MC, Rathmell JC, Lazar MA, Maris JM, Felsher DW, Hogenesch JB, Weljie AM, Dang CV. Altman BJ, et al. Among authors: rathmell jc. Cell Metab. 2015 Dec 1;22(6):1009-19. doi: 10.1016/j.cmet.2015.09.003. Epub 2015 Sep 17. Cell Metab. 2015. PMID: 26387865 Free PMC article.

2

The combined functions of proapoptotic Bcl-2 family members bak and bax are essential for normal development of multiple tissues.

Lindsten T, Ross AJ, King A, Zong WX, Rathmell JC, Shiels HA, Ulrich E, Waymire KG, Mahar P, Frauwirth K, Chen Y, Wei M, Eng VM, Adelman DM, Simon MC, Ma A, Golden JA, Evan G, Korsmeyer SJ, MacGregor GR, Thompson CB. Lindsten T, et al. Among authors: rathmell jc. Mol Cell. 2000 Dec;6(6):1389-99. doi: 10.1016/s1097-2765(00)00136-2. Mol Cell. 2000. PMID: 11163212 Free PMC article.

3

Isoform-specific requirement for Akt1 in the developmental regulation of cellular metabolism during lactation.

Boxer RB, Stairs DB, Dugan KD, Notarfrancesco KL, Portocarrero CP, Keister BA, Belka GK, Cho H, Rathmell JC, Thompson CB, Birnbaum MJ, Chodosh LA. Boxer RB, et al. Among authors: rathmell jc. Cell Metab. 2006 Dec;4(6):475-90. doi: 10.1016/j.cmet.2006.10.011. Cell Metab. 2006. PMID: 17141631 Free article.

4

Glycogen synthase kinase 3alpha and 3beta mediate a glucose-sensitive antiapoptotic signaling pathway to stabilize Mcl-1.

Zhao Y, Altman BJ, Coloff JL, Herman CE, Jacobs SR, Wieman HL, Wofford JA, Dimascio LN, Ilkayeva O, Kelekar A, Reya T, Rathmell JC. Zhao Y, et al. Among authors: rathmell jc. Mol Cell Biol. 2007 Jun;27(12):4328-39. doi: 10.1128/MCB.00153-07. Epub 2007 Mar 19. Mol Cell Biol. 2007. PMID: 17371841 Free PMC article.

5

Methed-up FOXOs can't in-Akt-ivate.

Michalek RD, Rathmell JC. Michalek RD, et al. Among authors: rathmell jc. Mol Cell. 2008 Oct 24;32(2):160-2. doi: 10.1016/j.molcel.2008.10.006. Mol Cell. 2008. PMID: 18951081 Free PMC article.

6

An essential role for the Glut1 PDZ-binding motif in growth factor regulation of Glut1 degradation and trafficking.

Wieman HL, Horn SR, Jacobs SR, Altman BJ, Kornbluth S, Rathmell JC. Wieman HL, et al. Among authors: rathmell jc. Biochem J. 2009 Mar 1;418(2):345-67. doi: 10.1042/BJ20081422. Biochem J. 2009. PMID: 19016655 Free PMC article.

7

Autophagy provides nutrients but can lead to Chop-dependent induction of Bim to sensitize growth factor-deprived cells to apoptosis.

Altman BJ, Wofford JA, Zhao Y, Coloff JL, Ferguson EC, Wieman HL, Day AE, Ilkayeva O, Rathmell JC. Altman BJ, et al. Among authors: rathmell jc. Mol Biol Cell. 2009 Feb;20(4):1180-91. doi: 10.1091/mbc.e08-08-0829. Epub 2008 Dec 24. Mol Biol Cell. 2009. PMID: 19109422 Free PMC article.

8

Autophagy: not good OR bad, but good AND bad.

Altman BJ, Rathmell JC. Altman BJ, et al. Among authors: rathmell jc. Autophagy. 2009 May;5(4):569-70. doi: 10.4161/auto.5.4.8254. Autophagy. 2009. PMID: 19398886 Free PMC article.

9

TGF-beta: a new role for an old AktTOR.

Goraksha-Hicks P, Rathmell JC. Goraksha-Hicks P, et al. Among authors: rathmell jc. Dev Cell. 2009 Jul;17(1):6-8. doi: 10.1016/j.devcel.2009.07.004. Dev Cell. 2009. PMID: 19619487 Free PMC article.

10

Aerobic glycolysis suppresses p53 activity to provide selective protection from apoptosis upon loss of growth signals or inhibition of BCR-Abl.

Mason EF, Zhao Y, Goraksha-Hicks P, Coloff JL, Gannon H, Jones SN, Rathmell JC. Mason EF, et al. Among authors: rathmell jc. Cancer Res. 2010 Oct 15;70(20):8066-76. doi: 10.1158/0008-5472.CAN-10-0608. Epub 2010 Sep 28. Cancer Res. 2010. PMID: 20876800 Free PMC article.

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