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Selective targeting of JAK/STAT signaling is potentiated by Bcl-xL blockade in IL-2-dependent adult T-cell leukemia.
Zhang M, Mathews Griner LA, Ju W, Duveau DY, Guha R, Petrus MN, Wen B, Maeda M, Shinn P, Ferrer M, Conlon KD, Bamford RN, O'Shea JJ, Thomas CJ, Waldmann TA. Zhang M, et al. Among authors: thomas cj. Proc Natl Acad Sci U S A. 2015 Oct 6;112(40):12480-5. doi: 10.1073/pnas.1516208112. Epub 2015 Sep 22. Proc Natl Acad Sci U S A. 2015. PMID: 26396258 Free PMC article.
Fluorescence spectroscopic profiling of compound libraries.
Simeonov A, Jadhav A, Thomas CJ, Wang Y, Huang R, Southall NT, Shinn P, Smith J, Austin CP, Auld DS, Inglese J. Simeonov A, et al. Among authors: thomas cj. J Med Chem. 2008 Apr 24;51(8):2363-71. doi: 10.1021/jm701301m. Epub 2008 Mar 26. J Med Chem. 2008. PMID: 18363325
Selective targeting of ITK blocks multiple steps of HIV replication.
Readinger JA, Schiralli GM, Jiang JK, Thomas CJ, August A, Henderson AJ, Schwartzberg PL. Readinger JA, et al. Among authors: thomas cj. Proc Natl Acad Sci U S A. 2008 May 6;105(18):6684-9. doi: 10.1073/pnas.0709659105. Epub 2008 Apr 28. Proc Natl Acad Sci U S A. 2008. PMID: 18443296 Free PMC article.
Examining the chirality, conformation and selective kinase inhibition of 3-((3R,4R)-4-methyl-3-(methyl(7H-pyrrolo[2,3-d]pyrimidin-4-yl)amino)piperidin-1-yl)-3-oxopropanenitrile (CP-690,550).
Jiang JK, Ghoreschi K, Deflorian F, Chen Z, Perreira M, Pesu M, Smith J, Nguyen DT, Liu EH, Leister W, Costanzi S, O'Shea JJ, Thomas CJ. Jiang JK, et al. Among authors: thomas cj. J Med Chem. 2008 Dec 25;51(24):8012-8. doi: 10.1021/jm801142b. J Med Chem. 2008. PMID: 19053756 Free PMC article.
Small-molecule agonists for the thyrotropin receptor stimulate thyroid function in human thyrocytes and mice.
Neumann S, Huang W, Titus S, Krause G, Kleinau G, Alberobello AT, Zheng W, Southall NT, Inglese J, Austin CP, Celi FS, Gavrilova O, Thomas CJ, Raaka BM, Gershengorn MC. Neumann S, et al. Among authors: thomas cj. Proc Natl Acad Sci U S A. 2009 Jul 28;106(30):12471-6. doi: 10.1073/pnas.0904506106. Epub 2009 Jul 10. Proc Natl Acad Sci U S A. 2009. PMID: 19592511 Free PMC article.
529 results