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The first trial of CIM331, a humanized antihuman interleukin-31 receptor A antibody, in healthy volunteers and patients with atopic dermatitis to evaluate safety, tolerability and pharmacokinetics of a single dose in a randomized, double-blind, placebo-controlled study.
Nemoto O, Furue M, Nakagawa H, Shiramoto M, Hanada R, Matsuki S, Imayama S, Kato M, Hasebe I, Taira K, Yamamoto M, Mihara R, Kabashima K, Ruzicka T, Hanifin J, Kumagai Y. Nemoto O, et al. Among authors: kumagai y. Br J Dermatol. 2016 Feb;174(2):296-304. doi: 10.1111/bjd.14207. Epub 2015 Dec 19. Br J Dermatol. 2016. PMID: 26409172 Clinical Trial.
Distinct phenotype of epidermolysis bullosa simplex with infantile migratory circinate erythema due to frameshift mutations in the V2 domain of KRT5.
Kumagai Y, Umegaki-Arao N, Sasaki T, Nakamura Y, Takahashi H, Ashida A, Tsunemi Y, Kawashima M, Shimizu A, Ishiko A, Nakamura K, Tsuchihashi H, Amagai M, Kubo A. Kumagai Y, et al. J Eur Acad Dermatol Venereol. 2017 May;31(5):e241-e243. doi: 10.1111/jdv.14005. Epub 2016 Nov 2. J Eur Acad Dermatol Venereol. 2017. PMID: 27730678 No abstract available.
A novel ryanodine receptor 2 inhibitor, M201-A, enhances natriuresis, renal function and lusi-inotropic actions: Preclinical and phase I study.
Kaneko N, Loughrey CM, Smith G, Matsuda R, Hasunuma T, Mark PB, Toda M, Shinozaki M, Otani N, Kayley S, Da Silva Costa A, Martin TP, Dobi S, Saxena P, Shimamoto K, Ishikawa T, Kambayashi R, Riddell A, Elliott EB, McCarroll CS, Sakai T, Mitsuhisa Y, Hirano S, Kitai T, Kusano K, Inoue Y, Nakamura M, Kikuchi M, Toyoda S, Taguchi I, Fujiwara T, Sugiyama A, Kumagai Y, Iwata K. Kaneko N, et al. Among authors: kumagai y. Br J Pharmacol. 2024 May 21. doi: 10.1111/bph.16379. Online ahead of print. Br J Pharmacol. 2024. PMID: 38773354
The Role of Momentum Partitioning in Covariance Ion Imaging Analysis.
Walmsley T, McManus JW, Kumagai Y, Nagaya K, Harries J, Iwayama H, Ashfold MNR, Britton M, Bucksbaum PH, Downes-Ward B, Driver T, Heathcote D, Hockett P, Howard AJ, Lee JWL, Liu Y, Kukk E, Milesevic D, Minns RS, Niozu A, Niskanen J, Orr-Ewing AJ, Owada S, Robertson PA, Rolles D, Rudenko A, Ueda K, Unwin J, Vallance C, Brouard M, Burt M, Allum F, Forbes R. Walmsley T, et al. Among authors: kumagai y. J Phys Chem A. 2024 May 7. doi: 10.1021/acs.jpca.4c00999. Online ahead of print. J Phys Chem A. 2024. PMID: 38713032
1,095 results