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Postnatal epigenetic regulation of intestinal stem cells requires DNA methylation and is guided by the microbiome.
Yu DH, Gadkari M, Zhou Q, Yu S, Gao N, Guan Y, Schady D, Roshan TN, Chen MH, Laritsky E, Ge Z, Wang H, Chen R, Westwater C, Bry L, Waterland RA, Moriarty C, Hwang C, Swennes AG, Moore SR, Shen L. Yu DH, et al. Among authors: shen l. Genome Biol. 2015 Sep 30;16:211. doi: 10.1186/s13059-015-0763-5. Genome Biol. 2015. PMID: 26420038 Free PMC article.
Methods of DNA methylation analysis.
Shen L, Waterland RA. Shen L, et al. Curr Opin Clin Nutr Metab Care. 2007 Sep;10(5):576-81. doi: 10.1097/MCO.0b013e3282bf6f43. Curr Opin Clin Nutr Metab Care. 2007. PMID: 17693740 Review.
Widespread and tissue specific age-related DNA methylation changes in mice.
Maegawa S, Hinkal G, Kim HS, Shen L, Zhang L, Zhang J, Zhang N, Liang S, Donehower LA, Issa JP. Maegawa S, et al. Among authors: shen l. Genome Res. 2010 Mar;20(3):332-40. doi: 10.1101/gr.096826.109. Epub 2010 Jan 27. Genome Res. 2010. PMID: 20107151 Free PMC article.
Epigenetic maturation in colonic mucosa continues beyond infancy in mice.
Kellermayer R, Balasa A, Zhang W, Lee S, Mirza S, Chakravarty A, Szigeti R, Laritsky E, Tatevian N, Smith CW, Shen L, Waterland RA. Kellermayer R, et al. Among authors: shen l. Hum Mol Genet. 2010 Jun 1;19(11):2168-76. doi: 10.1093/hmg/ddq095. Epub 2010 Mar 2. Hum Mol Genet. 2010. PMID: 20197410 Free PMC article.
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