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The lowering of hepatic fatty acid uptake improves liver function and insulin sensitivity without affecting hepatic fat content in humans.
Rigazio S, Lehto HR, Tuunanen H, Någren K, Kankaanpaa M, Simi C, Borra R, Naum AG, Parkkola R, Knuuti J, Nuutila P, Iozzo P. Rigazio S, et al. Among authors: borra r. Am J Physiol Endocrinol Metab. 2008 Aug;295(2):E413-9. doi: 10.1152/ajpendo.00744.2007. Epub 2008 May 27. Am J Physiol Endocrinol Metab. 2008. PMID: 18505832 Free article.
Effect of weight loss on liver free fatty acid uptake and hepatic insulin resistance.
Viljanen AP, Iozzo P, Borra R, Kankaanpää M, Karmi A, Lautamäki R, Järvisalo M, Parkkola R, Rönnemaa T, Guiducci L, Lehtimäki T, Raitakari OT, Mari A, Nuutila P. Viljanen AP, et al. Among authors: borra r. J Clin Endocrinol Metab. 2009 Jan;94(1):50-5. doi: 10.1210/jc.2008-1689. Epub 2008 Oct 28. J Clin Endocrinol Metab. 2009. PMID: 18957499
Fatty acid metabolism in the liver, measured by positron emission tomography, is increased in obese individuals.
Iozzo P, Bucci M, Roivainen A, Någren K, Järvisalo MJ, Kiss J, Guiducci L, Fielding B, Naum AG, Borra R, Virtanen K, Savunen T, Salvadori PA, Ferrannini E, Knuuti J, Nuutila P. Iozzo P, et al. Among authors: borra r. Gastroenterology. 2010 Sep;139(3):846-56, 856.e1-6. doi: 10.1053/j.gastro.2010.05.039. Epub 2010 May 25. Gastroenterology. 2010. PMID: 20685204
Liver and pancreatic fat content and metabolism in healthy monozygotic twins with discordant physical activity.
Hannukainen JC, Borra R, Linderborg K, Kallio H, Kiss J, Lepomäki V, Kalliokoski KK, Kujala UM, Kaprio J, Heinonen OJ, Komu M, Parkkola R, Ahotupa M, Lehtimäki T, Huupponen R, Iozzo P, Nuutila P. Hannukainen JC, et al. Among authors: borra r. J Hepatol. 2011 Mar;54(3):545-52. doi: 10.1016/j.jhep.2010.07.029. Epub 2010 Sep 19. J Hepatol. 2011. PMID: 21112658
Trimetazidine reduces endogenous free fatty acid oxidation and improves myocardial efficiency in obese humans.
Bucci M, Borra R, Någren K, Pärkkä JP, Del Ry S, Maggio R, Tuunanen H, Viljanen T, Cabiati M, Rigazio S, Taittonen M, Pagotto U, Parkkola R, Opie LH, Nuutila P, Knuuti J, Iozzo P. Bucci M, et al. Among authors: borra r. Cardiovasc Ther. 2012 Dec;30(6):333-41. doi: 10.1111/j.1755-5922.2011.00275.x. Epub 2011 Jul 31. Cardiovasc Ther. 2012. PMID: 21884010 Free article.
Prediction of non-alcoholic fatty-liver disease and liver fat content by serum molecular lipids.
Orešič M, Hyötyläinen T, Kotronen A, Gopalacharyulu P, Nygren H, Arola J, Castillo S, Mattila I, Hakkarainen A, Borra RJ, Honka MJ, Verrijken A, Francque S, Iozzo P, Leivonen M, Jaser N, Juuti A, Sørensen TI, Nuutila P, Van Gaal L, Yki-Järvinen H. Orešič M, et al. Diabetologia. 2013 Oct;56(10):2266-74. doi: 10.1007/s00125-013-2981-2. Epub 2013 Jul 4. Diabetologia. 2013. PMID: 23824212 Free PMC article.
Effect of bariatric surgery on liver glucose metabolism in morbidly obese diabetic and non-diabetic patients.
Immonen H, Hannukainen JC, Iozzo P, Soinio M, Salminen P, Saunavaara V, Borra R, Parkkola R, Mari A, Lehtimäki T, Pham T, Laine J, Kärjä V, Pihlajamäki J, Nelimarkka L, Nuutila P. Immonen H, et al. Among authors: borra r. J Hepatol. 2014 Feb;60(2):377-83. doi: 10.1016/j.jhep.2013.09.012. Epub 2013 Sep 20. J Hepatol. 2014. PMID: 24060855 Clinical Trial.
Effect of aerobic exercise and low carbohydrate diet on pre-diabetic non-alcoholic fatty liver disease in postmenopausal women and middle aged men--the role of gut microbiota composition: study protocol for the AELC randomized controlled trial.
Liu WY, Lu DJ, Du XM, Sun JQ, Ge J, Wang RW, Wang R, Zou J, Xu C, Ren J, Wen XF, Liu Y, Cheng SM, Tan X, Pekkala S, Munukka E, Wiklund P, Chen YQ, Gu Q, Xia ZC, Liu JJ, Liu WB, Chen XB, Zhang YM, Li R, Borra RJ, Yao JX, Chen PJ, Cheng S. Liu WY, et al. Among authors: borra rj. BMC Public Health. 2014 Jan 17;14:48. doi: 10.1186/1471-2458-14-48. BMC Public Health. 2014. PMID: 24438438 Free PMC article. Clinical Trial.
182 results