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Conversion of ATP to adenosine by CD39 and CD73 in multiple myeloma can be successfully targeted together with adenosine receptor A2A blockade.
Yang R, Elsaadi S, Misund K, Abdollahi P, Vandsemb EN, Moen SH, Kusnierczyk A, Slupphaug G, Standal T, Waage A, Slørdahl TS, Rø TB, Rustad E, Sundan A, Hay C, Cooper Z, Schuller AG, Woessner R, Borodovsky A, Menu E, Børset M, Sponaas AM. Yang R, et al. Among authors: sponaas am. J Immunother Cancer. 2020 May;8(1):e000610. doi: 10.1136/jitc-2020-000610. J Immunother Cancer. 2020. PMID: 32409420 Free PMC article.
Clonal evolution after treatment pressure in multiple myeloma: heterogenous genomic aberrations and transcriptomic convergence.
Misund K, Hofste Op Bruinink D, Coward E, Hoogenboezem RM, Rustad EH, Sanders MA, Rye M, Sponaas AM, van der Holt B, Zweegman S, Hovig E, Meza-Zepeda LA, Sundan A, Myklebost O, Sonneveld P, Waage A. Misund K, et al. Among authors: sponaas am. Leukemia. 2022 Jul;36(7):1887-1897. doi: 10.1038/s41375-022-01597-y. Epub 2022 May 28. Leukemia. 2022. PMID: 35643867 Free PMC article.
Bone Morphogenetic Protein 4 Gene Therapy in Mice Inhibits Myeloma Tumor Growth, But Has a Negative Impact on Bone.
Westhrin M, Holien T, Zahoor M, Moen SH, Buene G, Størdal B, Hella H, Yuan H, de Bruijn JD, Martens A, Groen RW, Bosch F, Smith U, Sponaas AM, Sundan A, Standal T. Westhrin M, et al. Among authors: sponaas am. JBMR Plus. 2019 Nov 22;4(1):e10247. doi: 10.1002/jbm4.10247. eCollection 2020 Jan. JBMR Plus. 2019. PMID: 31956851 Free PMC article.
Intracellular IL-32 regulates mitochondrial metabolism, proliferation, and differentiation of malignant plasma cells.
Aass KR, Mjelle R, Kastnes MH, Tryggestad SS, van den Brink LM, Aass Roseth I, Westhrin M, Zahoor M, Moen SH, Vikene Nedal TM, Buene G, Misund K, Sponaas AM, Ma Q, Sundan A, Groen RW, Slørdahl TS, Waage A, Standal T. Aass KR, et al. Among authors: sponaas am. iScience. 2021 Dec 13;25(1):103605. doi: 10.1016/j.isci.2021.103605. eCollection 2022 Jan 21. iScience. 2021. PMID: 35005550 Free PMC article.
43 results