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Partitioning heritability of regulatory and cell-type-specific variants across 11 common diseases.
Gusev A, Lee SH, Trynka G, Finucane H, Vilhjálmsson BJ, Xu H, Zang C, Ripke S, Bulik-Sullivan B, Stahl E; Schizophrenia Working Group of the Psychiatric Genomics Consortium; SWE-SCZ Consortium; Kähler AK, Hultman CM, Purcell SM, McCarroll SA, Daly M, Pasaniuc B, Sullivan PF, Neale BM, Wray NR, Raychaudhuri S, Price AL; Schizophrenia Working Group of the Psychiatric Genomics Consortium; SWE-SCZ Consortium. Gusev A, et al. Am J Hum Genet. 2014 Nov 6;95(5):535-52. doi: 10.1016/j.ajhg.2014.10.004. Epub 2014 Nov 6. Am J Hum Genet. 2014. PMID: 25439723 Free PMC article.
Modeling Linkage Disequilibrium Increases Accuracy of Polygenic Risk Scores.
Vilhjálmsson BJ, Yang J, Finucane HK, Gusev A, Lindström S, Ripke S, Genovese G, Loh PR, Bhatia G, Do R, Hayeck T, Won HH; Schizophrenia Working Group of the Psychiatric Genomics Consortium, Discovery, Biology, and Risk of Inherited Variants in Breast Cancer (DRIVE) study; Kathiresan S, Pato M, Pato C, Tamimi R, Stahl E, Zaitlen N, Pasaniuc B, Belbin G, Kenny EE, Schierup MH, De Jager P, Patsopoulos NA, McCarroll S, Daly M, Purcell S, Chasman D, Neale B, Goddard M, Visscher PM, Kraft P, Patterson N, Price AL. Vilhjálmsson BJ, et al. Am J Hum Genet. 2015 Oct 1;97(4):576-92. doi: 10.1016/j.ajhg.2015.09.001. Am J Hum Genet. 2015. PMID: 26430803 Free PMC article.
A phenotype-based genetic association study reveals the contribution of neuregulin1 gene variants to age of onset and positive symptom severity in schizophrenia.
Papiol S, Begemann M, Rosenberger A, Friedrichs H, Ribbe K, Grube S, Schwab MH, Jahn H, Gunkel S, Benseler F, Nave KA, Ehrenreich H. Papiol S, et al. Among authors: begemann m. Am J Med Genet B Neuropsychiatr Genet. 2011 Apr;156B(3):340-5. doi: 10.1002/ajmg.b.31168. Epub 2011 Jan 13. Am J Med Genet B Neuropsychiatr Genet. 2011. PMID: 21234898
Mild expression differences of MECP2 influencing aggressive social behavior.
Tantra M, Hammer C, Kästner A, Dahm L, Begemann M, Bodda C, Hammerschmidt K, Giegling I, Stepniak B, Castillo Venzor A, Konte B, Erbaba B, Hartmann A, Tarami A, Schulz-Schaeffer W, Rujescu D, Mannan AU, Ehrenreich H. Tantra M, et al. Among authors: begemann m. EMBO Mol Med. 2014 May;6(5):662-84. doi: 10.1002/emmm.201303744. EMBO Mol Med. 2014. PMID: 24648499 Free PMC article.
Genome-wide association study reveals greater polygenic loading for schizophrenia in cases with a family history of illness.
Bigdeli TB, Ripke S, Bacanu SA, Lee SH, Wray NR, Gejman PV, Rietschel M, Cichon S, St Clair D, Corvin A, Kirov G, McQuillin A, Gurling H, Rujescu D, Andreassen OA, Werge T, Blackwood DH, Pato CN, Pato MT, Malhotra AK, O'Donovan MC, Kendler KS, Fanous AH; Schizophrenia Working Group of the Psychiatric Genomics Consortium. Bigdeli TB, et al. Am J Med Genet B Neuropsychiatr Genet. 2016 Mar;171B(2):276-89. doi: 10.1002/ajmg.b.32402. Epub 2015 Dec 11. Am J Med Genet B Neuropsychiatr Genet. 2016. PMID: 26663532 Free PMC article.
Common variants of the genes encoding erythropoietin and its receptor modulate cognitive performance in schizophrenia.
Kästner A, Grube S, El-Kordi A, Stepniak B, Friedrichs H, Sargin D, Schwitulla J, Begemann M, Giegling I, Miskowiak KW, Sperling S, Hannke K, Ramin A, Heinrich R, Gefeller O, Nave KA, Rujescu D, Ehrenreich H. Kästner A, et al. Among authors: begemann m. Mol Med. 2012 Sep 7;18(1):1029-40. doi: 10.2119/molmed.2012.00190. Mol Med. 2012. PMID: 22669473 Free PMC article.
264 results