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Multiplicative interaction of functional inflammasome genetic variants in determining the risk of gout.
McKinney C, Stamp LK, Dalbeth N, Topless RK, Day RO, Kannangara DR, Williams KM, Janssen M, Jansen TL, Joosten LA, Radstake TR, Riches PL, Tausche AK, Lioté F, So A, Merriman TR. McKinney C, et al. Among authors: joosten la. Arthritis Res Ther. 2015 Oct 13;17:288. doi: 10.1186/s13075-015-0802-3. Arthritis Res Ther. 2015. PMID: 26462562 Free PMC article.
Increased expression of Fcgamma receptors II and III on macrophages of rheumatoid arthritis patients results in higher production of tumor necrosis factor alpha and matrix metalloproteinase.
Blom AB, Radstake TR, Holthuysen AE, Slöetjes AW, Pesman GJ, Sweep FG, van de Loo FA, Joosten LA, Barrera P, van Lent PL, van den Berg WB. Blom AB, et al. Among authors: joosten la. Arthritis Rheum. 2003 Apr;48(4):1002-14. doi: 10.1002/art.10871. Arthritis Rheum. 2003. PMID: 12687542 Free article.
The Toll-like receptor 4 Asp299Gly functional variant is associated with decreased rheumatoid arthritis disease susceptibility but does not influence disease severity and/or outcome.
Radstake TR, Franke B, Hanssen S, Netea MG, Welsing P, Barrera P, Joosten LA, van Riel PL, van den Berg WB. Radstake TR, et al. Among authors: joosten la. Arthritis Rheum. 2004 Mar;50(3):999-1001. doi: 10.1002/art.20114. Arthritis Rheum. 2004. PMID: 15022344 Free article. No abstract available.
The expression of toll-like receptors 3 and 7 in rheumatoid arthritis synovium is increased and costimulation of toll-like receptors 3, 4, and 7/8 results in synergistic cytokine production by dendritic cells.
Roelofs MF, Joosten LA, Abdollahi-Roodsaz S, van Lieshout AW, Sprong T, van den Hoogen FH, van den Berg WB, Radstake TR. Roelofs MF, et al. Among authors: joosten la. Arthritis Rheum. 2005 Aug;52(8):2313-22. doi: 10.1002/art.21278. Arthritis Rheum. 2005. PMID: 16052591 Free article.
IL-32, a proinflammatory cytokine in rheumatoid arthritis.
Joosten LA, Netea MG, Kim SH, Yoon DY, Oppers-Walgreen B, Radstake TR, Barrera P, van de Loo FA, Dinarello CA, van den Berg WB. Joosten LA, et al. Proc Natl Acad Sci U S A. 2006 Feb 28;103(9):3298-303. doi: 10.1073/pnas.0511233103. Epub 2006 Feb 21. Proc Natl Acad Sci U S A. 2006. PMID: 16492735 Free PMC article.
765 results