Zhu J - Search Results

1

Histone methyltransferase SETDB1 regulates liver cancer cell growth through methylation of p53.

Fei Q, Shang K, Zhang J, Chuai S, Kong D, Zhou T, Fu S, Liang Y, Li C, Chen Z, Zhao Y, Yu Z, Huang Z, Hu M, Ying H, Chen Z, Zhang Y, Xing F, Zhu J, Xu H, Zhao K, Lu C, Atadja P, Xiao ZX, Li E, Shou J. Fei Q, et al. Among authors: zhu j. Nat Commun. 2015 Oct 16;6:8651. doi: 10.1038/ncomms9651. Nat Commun. 2015. PMID: 26471002 Free PMC article.

2

Structure of human SMYD2 protein reveals the basis of p53 tumor suppressor methylation.

Wang L, Li L, Zhang H, Luo X, Dai J, Zhou S, Gu J, Zhu J, Atadja P, Lu C, Li E, Zhao K. Wang L, et al. Among authors: zhu j. J Biol Chem. 2011 Nov 4;286(44):38725-38737. doi: 10.1074/jbc.M111.262410. Epub 2011 Aug 31. J Biol Chem. 2011. PMID: 21880715 Free PMC article.

3

Targeting MLL1 H3K4 methyltransferase activity in mixed-lineage leukemia.

Cao F, Townsend EC, Karatas H, Xu J, Li L, Lee S, Liu L, Chen Y, Ouillette P, Zhu J, Hess JL, Atadja P, Lei M, Qin ZS, Malek S, Wang S, Dou Y. Cao F, et al. Among authors: zhu j. Mol Cell. 2014 Jan 23;53(2):247-61. doi: 10.1016/j.molcel.2013.12.001. Epub 2014 Jan 2. Mol Cell. 2014. PMID: 24389101 Free PMC article.

4

Targeting androgen receptor phase separation to overcome antiandrogen resistance.

Xie J, He H, Kong W, Li Z, Gao Z, Xie D, Sun L, Fan X, Jiang X, Zheng Q, Li G, Zhu J, Zhu G. Xie J, et al. Among authors: zhu g, zhu j. Nat Chem Biol. 2022 Dec;18(12):1341-1350. doi: 10.1038/s41589-022-01151-y. Epub 2022 Oct 13. Nat Chem Biol. 2022. PMID: 36229685

5

Novel Triapine Derivative Induces Copper-Dependent Cell Death in Hematopoietic Cancers.

Chen G, Niu C, Yi J, Sun L, Cao H, Fang Y, Jin T, Li Y, Lou C, Kang J, Wei W, Zhu J. Chen G, et al. Among authors: zhu j. J Med Chem. 2019 Mar 28;62(6):3107-3121. doi: 10.1021/acs.jmedchem.8b01996. Epub 2019 Mar 18. J Med Chem. 2019. PMID: 30835473

6

Discovery of new small molecule inhibitors targeting isocitrate dehydrogenase 1 (IDH1) with blood-brain barrier penetration.

Cao H, Zhu G, Sun L, Chen G, Ma X, Luo X, Zhu J. Cao H, et al. Among authors: zhu g, zhu j. Eur J Med Chem. 2019 Dec 1;183:111694. doi: 10.1016/j.ejmech.2019.111694. Epub 2019 Sep 13. Eur J Med Chem. 2019. PMID: 31561044

7

Phase separation ability and phosphatase activity of the SHP1-R360E mutant.

Zhang Q, Kong W, Zhu T, Zhu G, Zhu J, Kong X, Du Y. Zhang Q, et al. Among authors: zhu t, zhu g, zhu j. Biochem Biophys Res Commun. 2022 Apr 16;600:150-155. doi: 10.1016/j.bbrc.2022.02.070. Epub 2022 Feb 22. Biochem Biophys Res Commun. 2022. PMID: 35219918

8

A novel partially open state of SHP2 points to a "multiple gear" regulation mechanism.

Tao Y, Xie J, Zhong Q, Wang Y, Zhang S, Luo F, Wen F, Xie J, Zhao J, Sun X, Long H, Ma J, Zhang Q, Long J, Fang X, Lu Y, Li D, Li M, Zhu J, Sun B, Li G, Diao J, Liu C. Tao Y, et al. Among authors: zhu j. J Biol Chem. 2021 Jan-Jun;296:100538. doi: 10.1016/j.jbc.2021.100538. Epub 2021 Mar 12. J Biol Chem. 2021. PMID: 33722610 Free PMC article.

9

Screening inhibitors for blocking UHRF1-methylated DNA interaction with capillary electrophoresis.

Lou C, Ye X, Chen G, Zhu J, Kang J. Lou C, et al. Among authors: zhu j. J Chromatogr A. 2021 Jan 11;1636:461790. doi: 10.1016/j.chroma.2020.461790. Epub 2020 Dec 9. J Chromatogr A. 2021. PMID: 33340746

10

Phase Separation of Disease-Associated SHP2 Mutants Underlies MAPK Hyperactivation.

Zhu G, Xie J, Kong W, Xie J, Li Y, Du L, Zheng Q, Sun L, Guan M, Li H, Zhu T, He H, Liu Z, Xia X, Kan C, Tao Y, Shen HC, Li D, Wang S, Yu Y, Yu ZH, Zhang ZY, Liu C, Zhu J. Zhu G, et al. Among authors: zhu t, zhu j. Cell. 2020 Oct 15;183(2):490-502.e18. doi: 10.1016/j.cell.2020.09.002. Epub 2020 Sep 30. Cell. 2020. PMID: 33002410 Free PMC article.

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