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A chemical biology approach reveals a dependency of glioblastoma on biotin distribution.
Yoon J, Grinchuk OV, Kannan S, Ang MJY, Li Z, Tay EXY, Lok KZ, Lee BWL, Chuah YH, Chia K, Tirado Magallanes R, Liu C, Zhao H, Hor JH, Lim JJ, Benoukraf T, Toh TB, Chow EK, Kovalik JP, Ching J, Ng SY, Koh MJ, Liu X, Verma CS, Ong DST. Yoon J, et al. Among authors: grinchuk ov. Sci Adv. 2021 Sep 3;7(36):eabf6033. doi: 10.1126/sciadv.abf6033. Epub 2021 Sep 3. Sci Adv. 2021. PMID: 34516894 Free PMC article.
E2F and STAT3 provide transcriptional synergy for histone variant H2AZ activation to sustain glioblastoma chromatin accessibility and tumorigenicity.
Yoon J, Grinchuk OV, Tirado-Magallanes R, Ngian ZK, Tay EXY, Chuah YH, Lee BWL, Feng J, Crasta KC, Ong CT, Benoukraf T, Ong DST. Yoon J, et al. Among authors: grinchuk ov. Cell Death Differ. 2022 Jul;29(7):1379-1394. doi: 10.1038/s41418-021-00926-5. Epub 2022 Jan 20. Cell Death Differ. 2022. PMID: 35058574 Free PMC article.
PHF2 regulates genome topology and DNA replication in neural stem cells via cohesin.
Feng J, Chuah YH, Liang Y, Cipta NO, Zeng Y, Warrier T, Elfar GARE, Yoon J, Grinchuk OV, Tay EXY, Lok KZ, Zheng ZQ, Khong ZJ, Chong ZS, Teo J, Sanford EM, Neo CJY, Chiu HY, Leung JY, Wang LC, Lim YT, Zhao T, Sobota RM, Crasta KC, Tergaonkar V, Taneja R, Ng SY, Cheok CF, Ling SC, Loh YH, Ong DST. Feng J, et al. Among authors: grinchuk ov. Nucleic Acids Res. 2024 May 29:gkae457. doi: 10.1093/nar/gkae457. Online ahead of print. Nucleic Acids Res. 2024. PMID: 38808662
22 results