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The transcriptional landscape of age in human peripheral blood.
Peters MJ, Joehanes R, Pilling LC, Schurmann C, Conneely KN, Powell J, Reinmaa E, Sutphin GL, Zhernakova A, Schramm K, Wilson YA, Kobes S, Tukiainen T; NABEC/UKBEC Consortium; Ramos YF, Göring HH, Fornage M, Liu Y, Gharib SA, Stranger BE, De Jager PL, Aviv A, Levy D, Murabito JM, Munson PJ, Huan T, Hofman A, Uitterlinden AG, Rivadeneira F, van Rooij J, Stolk L, Broer L, Verbiest MM, Jhamai M, Arp P, Metspalu A, Tserel L, Milani L, Samani NJ, Peterson P, Kasela S, Codd V, Peters A, Ward-Caviness CK, Herder C, Waldenberger M, Roden M, Singmann P, Zeilinger S, Illig T, Homuth G, Grabe HJ, Völzke H, Steil L, Kocher T, Murray A, Melzer D, Yaghootkar H, Bandinelli S, Moses EK, Kent JW, Curran JE, Johnson MP, Williams-Blangero S, Westra HJ, McRae AF, Smith JA, Kardia SL, Hovatta I, Perola M, Ripatti S, Salomaa V, Henders AK, Martin NG, Smith AK, Mehta D, Binder EB, Nylocks KM, Kennedy EM, Klengel T, Ding J, Suchy-Dicey AM, Enquobahrie DA, Brody J, Rotter JI, Chen YD, Houwing-Duistermaat J, Kloppenburg M, Slagboom PE, Helmer Q, den Hollander W, Bean S, Raj T, Bakhshi N, Wang QP, Oyston LJ, Psaty BM, Tracy RP, Montgomery GW, Turner ST, Blangero J, Meulenbelt I, Ressler KJ, Yang J, F… See abstract for full author list ➔ Peters MJ, et al. Among authors: sutphin gl. Nat Commun. 2015 Oct 22;6:8570. doi: 10.1038/ncomms9570. Nat Commun. 2015. PMID: 26490707 Free PMC article.
Caenorhabditis elegans orthologs of human genes differentially expressed with age are enriched for determinants of longevity.
Sutphin GL, Backer G, Sheehan S, Bean S, Corban C, Liu T, Peters MJ, van Meurs JBJ, Murabito JM, Johnson AD, Korstanje R; Cohorts for Heart and Aging Research in Genomic Epidemiology (CHARGE) Consortium Gene Expression Working Group. Sutphin GL, et al. Aging Cell. 2017 Aug;16(4):672-682. doi: 10.1111/acel.12595. Epub 2017 Apr 12. Aging Cell. 2017. PMID: 28401650 Free PMC article.
On the benefits of the tryptophan metabolite 3-hydroxyanthranilic acid in Caenorhabditis elegans and mouse aging.
Dang H, Castro-Portuguez R, Espejo L, Backer G, Freitas S, Spence E, Meyers J, Shuck K, Gardea EA, Chang LM, Balsa J, Thorns N, Corban C, Liu T, Bean S, Sheehan S, Korstanje R, Sutphin GL. Dang H, et al. Among authors: sutphin gl. Nat Commun. 2023 Dec 14;14(1):8338. doi: 10.1038/s41467-023-43527-1. Nat Commun. 2023. PMID: 38097593 Free PMC article.
Transcription errors induce proteotoxic stress and shorten cellular lifespan.
Vermulst M, Denney AS, Lang MJ, Hung CW, Moore S, Moseley MA, Thompson JW, Madden V, Gauer J, Wolfe KJ, Summers DW, Schleit J, Sutphin GL, Haroon S, Holczbauer A, Caine J, Jorgenson J, Cyr D, Kaeberlein M, Strathern JN, Duncan MC, Erie DA. Vermulst M, et al. Among authors: sutphin gl. Nat Commun. 2015 Aug 25;6:8065. doi: 10.1038/ncomms9065. Nat Commun. 2015. PMID: 26304740 Free PMC article.
Effects of a Global Rab27a Null Mutation on Murine PVAT and Cardiovascular Function.
Soucy A, Potts C, Kaija A, Harrington A, McGilvrey M, Sutphin GL, Korstanje R, Tero B, Seeker J, Pinz I, Vary C, Ryzhova L, Liaw L. Soucy A, et al. Among authors: sutphin gl. Arterioscler Thromb Vasc Biol. 2024 Apr 25. doi: 10.1161/ATVBAHA.124.320969. Online ahead of print. Arterioscler Thromb Vasc Biol. 2024. PMID: 38660803
Absence of effects of Sir2 overexpression on lifespan in C. elegans and Drosophila.
Burnett C, Valentini S, Cabreiro F, Goss M, Somogyvári M, Piper MD, Hoddinott M, Sutphin GL, Leko V, McElwee JJ, Vazquez-Manrique RP, Orfila AM, Ackerman D, Au C, Vinti G, Riesen M, Howard K, Neri C, Bedalov A, Kaeberlein M, Soti C, Partridge L, Gems D. Burnett C, et al. Among authors: sutphin gl. Nature. 2011 Sep 21;477(7365):482-5. doi: 10.1038/nature10296. Nature. 2011. PMID: 21938067 Free PMC article.
Replicative life span analysis in budding yeast.
Sutphin GL, Delaney JR, Kaeberlein M. Sutphin GL, et al. Methods Mol Biol. 2014;1205:341-57. doi: 10.1007/978-1-4939-1363-3_20. Methods Mol Biol. 2014. PMID: 25213254
37 results