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Modelling kidney disease with CRISPR-mutant kidney organoids derived from human pluripotent epiblast spheroids.
Freedman BS, Brooks CR, Lam AQ, Fu H, Morizane R, Agrawal V, Saad AF, Li MK, Hughes MR, Werff RV, Peters DT, Lu J, Baccei A, Siedlecki AM, Valerius MT, Musunuru K, McNagny KM, Steinman TI, Zhou J, Lerou PH, Bonventre JV. Freedman BS, et al. Among authors: lerou ph. Nat Commun. 2015 Oct 23;6:8715. doi: 10.1038/ncomms9715. Nat Commun. 2015. PMID: 26493500 Free PMC article.
Human embryonic stem cell derivation from poor-quality embryos.
Lerou PH, Yabuuchi A, Huo H, Takeuchi A, Shea J, Cimini T, Ince TA, Ginsburg E, Racowsky C, Daley GQ. Lerou PH, et al. Nat Biotechnol. 2008 Feb;26(2):212-4. doi: 10.1038/nbt1378. Epub 2008 Jan 27. Nat Biotechnol. 2008. PMID: 18223642
Generation of human-induced pluripotent stem cells.
Park IH, Lerou PH, Zhao R, Huo H, Daley GQ. Park IH, et al. Among authors: lerou ph. Nat Protoc. 2008;3(7):1180-6. doi: 10.1038/nprot.2008.92. Nat Protoc. 2008. PMID: 18600223
Induced pluripotent stem cells with a mitochondrial DNA deletion.
Cherry AB, Gagne KE, McLoughlin EM, Baccei A, Gorman B, Hartung O, Miller JD, Zhang J, Zon RL, Ince TA, Neufeld EJ, Lerou PH, Fleming MD, Daley GQ, Agarwal S. Cherry AB, et al. Among authors: lerou ph. Stem Cells. 2013 Jul;31(7):1287-97. doi: 10.1002/stem.1354. Stem Cells. 2013. PMID: 23400930 Free PMC article.
High mitochondrial priming sensitizes hESCs to DNA-damage-induced apoptosis.
Liu JC, Guan X, Ryan JA, Rivera AG, Mock C, Agrawal V, Letai A, Lerou PH, Lahav G. Liu JC, et al. Among authors: lerou ph. Cell Stem Cell. 2013 Oct 3;13(4):483-91. doi: 10.1016/j.stem.2013.07.018. Epub 2013 Aug 15. Cell Stem Cell. 2013. PMID: 23954752 Free PMC article.
46 results