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Generation of functional human serotonergic neurons from fibroblasts.
Vadodaria KC, Mertens J, Paquola A, Bardy C, Li X, Jappelli R, Fung L, Marchetto MC, Hamm M, Gorris M, Koch P, Gage FH. Vadodaria KC, et al. Among authors: paquola a. Mol Psychiatry. 2016 Jan;21(1):49-61. doi: 10.1038/mp.2015.161. Epub 2015 Oct 27. Mol Psychiatry. 2016. PMID: 26503761
Differential L1 regulation in pluripotent stem cells of humans and apes.
Marchetto MCN, Narvaiza I, Denli AM, Benner C, Lazzarini TA, Nathanson JL, Paquola ACM, Desai KN, Herai RH, Weitzman MD, Yeo GW, Muotri AR, Gage FH. Marchetto MCN, et al. Among authors: paquola acm. Nature. 2013 Nov 28;503(7477):525-529. doi: 10.1038/nature12686. Epub 2013 Oct 23. Nature. 2013. PMID: 24153179 Free PMC article.
Directly Reprogrammed Human Neurons Retain Aging-Associated Transcriptomic Signatures and Reveal Age-Related Nucleocytoplasmic Defects.
Mertens J, Paquola ACM, Ku M, Hatch E, Böhnke L, Ladjevardi S, McGrath S, Campbell B, Lee H, Herdy JR, Gonçalves JT, Toda T, Kim Y, Winkler J, Yao J, Hetzer MW, Gage FH. Mertens J, et al. Cell Stem Cell. 2015 Dec 3;17(6):705-718. doi: 10.1016/j.stem.2015.09.001. Epub 2015 Oct 8. Cell Stem Cell. 2015. PMID: 26456686 Free PMC article.
The different moods of human serotonergic neurons.
Vadodaria KC, Mertens J, Paquola A, Bardy C, Li X, Jappelli R, Fung L, Marchetto MC, Hamm M, Gorris M, Koch P, Gage FH. Vadodaria KC, et al. Among authors: paquola a. Mol Psychiatry. 2016 Jan;21(1):3. doi: 10.1038/mp.2015.202. Mol Psychiatry. 2016. PMID: 26678308 No abstract available.
Nuclear RNA-seq of single neurons reveals molecular signatures of activation.
Lacar B, Linker SB, Jaeger BN, Krishnaswami SR, Barron JJ, Kelder MJE, Parylak SL, Paquola ACM, Venepally P, Novotny M, O'Connor C, Fitzpatrick C, Erwin JA, Hsu JY, Husband D, McConnell MJ, Lasken R, Gage FH. Lacar B, et al. Among authors: paquola acm. Nat Commun. 2016 Apr 19;7:11022. doi: 10.1038/ncomms11022. Nat Commun. 2016. PMID: 27090946 Free PMC article.
L1-associated genomic regions are deleted in somatic cells of the healthy human brain.
Erwin JA, Paquola AC, Singer T, Gallina I, Novotny M, Quayle C, Bedrosian TA, Alves FI, Butcher CR, Herdy JR, Sarkar A, Lasken RS, Muotri AR, Gage FH. Erwin JA, et al. Among authors: paquola ac. Nat Neurosci. 2016 Dec;19(12):1583-1591. doi: 10.1038/nn.4388. Epub 2016 Sep 12. Nat Neurosci. 2016. PMID: 27618310 Free PMC article.
Insights into the role of somatic mosaicism in the brain.
Paquola ACM, Erwin JA, Gage FH. Paquola ACM, et al. Curr Opin Syst Biol. 2017 Feb;1:90-94. doi: 10.1016/j.coisb.2016.12.004. Epub 2016 Dec 9. Curr Opin Syst Biol. 2017. PMID: 29226270 Free PMC article.
Efficient Generation of CA3 Neurons from Human Pluripotent Stem Cells Enables Modeling of Hippocampal Connectivity In Vitro.
Sarkar A, Mei A, Paquola ACM, Stern S, Bardy C, Klug JR, Kim S, Neshat N, Kim HJ, Ku M, Shokhirev MN, Adamowicz DH, Marchetto MC, Jappelli R, Erwin JA, Padmanabhan K, Shtrahman M, Jin X, Gage FH. Sarkar A, et al. Among authors: paquola acm. Cell Stem Cell. 2018 May 3;22(5):684-697.e9. doi: 10.1016/j.stem.2018.04.009. Cell Stem Cell. 2018. PMID: 29727680 Free PMC article.
60 results