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Oxylipid Profile of Low-Dose Aspirin Exposure: A Pharmacometabolomics Study.
Ellero-Simatos S, Beitelshees AL, Lewis JP, Yerges-Armstrong LM, Georgiades A, Dane A, Harms AC, Strassburg K, Guled F, Hendriks MM, Horenstein RB, Shuldiner AR, Hankemeier T, Kaddurah-Daouk R; Pharmacometabolomics Research Network. Ellero-Simatos S, et al. Among authors: dane a. J Am Heart Assoc. 2015 Oct 26;4(10):e002203. doi: 10.1161/JAHA.115.002203. J Am Heart Assoc. 2015. PMID: 26504148 Free PMC article. Clinical Trial.
Purine pathway implicated in mechanism of resistance to aspirin therapy: pharmacometabolomics-informed pharmacogenomics.
Yerges-Armstrong LM, Ellero-Simatos S, Georgiades A, Zhu H, Lewis JP, Horenstein RB, Beitelshees AL, Dane A, Reijmers T, Hankemeier T, Fiehn O, Shuldiner AR, Kaddurah-Daouk R. Yerges-Armstrong LM, et al. Among authors: dane a. Clin Pharmacol Ther. 2013 Oct;94(4):525-32. doi: 10.1038/clpt.2013.119. Epub 2013 Jun 11. Clin Pharmacol Ther. 2013. PMID: 23839601 Free PMC article. Clinical Trial.
Pharmacometabolomics reveals that serotonin is implicated in aspirin response variability.
Ellero-Simatos S, Lewis JP, Georgiades A, Yerges-Armstrong LM, Beitelshees AL, Horenstein RB, Dane A, Harms AC, Ramaker R, Vreeken RJ, Perry CG, Zhu H, Sànchez CL, Kuhn C, Ortel TL, Shuldiner AR, Hankemeier T, Kaddurah-Daouk R. Ellero-Simatos S, et al. Among authors: dane a. CPT Pharmacometrics Syst Pharmacol. 2014 Jul 16;3(7):e125. doi: 10.1038/psp.2014.22. CPT Pharmacometrics Syst Pharmacol. 2014. PMID: 25029353 Free PMC article.
Quantitative profiling of oxylipins through comprehensive LC-MS/MS analysis: application in cardiac surgery.
Strassburg K, Huijbrechts AM, Kortekaas KA, Lindeman JH, Pedersen TL, Dane A, Berger R, Brenkman A, Hankemeier T, van Duynhoven J, Kalkhoven E, Newman JW, Vreeken RJ. Strassburg K, et al. Among authors: dane a. Anal Bioanal Chem. 2012 Sep;404(5):1413-26. doi: 10.1007/s00216-012-6226-x. Epub 2012 Jul 20. Anal Bioanal Chem. 2012. PMID: 22814969 Free PMC article.
171 results