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Identification of Small Molecule Inhibitors of Tau Aggregation by Targeting Monomeric Tau As a Potential Therapeutic Approach for Tauopathies.
Pickhardt M, Neumann T, Schwizer D, Callaway K, Vendruscolo M, Schenk D, St George-Hyslop P, Mandelkow EM, Dobson CM, McConlogue L, Mandelkow E, Tóth G. Pickhardt M, et al. Among authors: callaway k. Curr Alzheimer Res. 2015;12(9):814-28. doi: 10.2174/156720501209151019104951. Curr Alzheimer Res. 2015. PMID: 26510979 Free PMC article.
Targeting the intrinsically disordered structural ensemble of α-synuclein by small molecules as a potential therapeutic strategy for Parkinson's disease.
Tóth G, Gardai SJ, Zago W, Bertoncini CW, Cremades N, Roy SL, Tambe MA, Rochet JC, Galvagnion C, Skibinski G, Finkbeiner S, Bova M, Regnstrom K, Chiou SS, Johnston J, Callaway K, Anderson JP, Jobling MF, Buell AK, Yednock TA, Knowles TP, Vendruscolo M, Christodoulou J, Dobson CM, Schenk D, McConlogue L. Tóth G, et al. Among authors: callaway k. PLoS One. 2014 Feb 14;9(2):e87133. doi: 10.1371/journal.pone.0087133. eCollection 2014. PLoS One. 2014. PMID: 24551051 Free PMC article.
Label free fragment screening using surface plasmon resonance as a tool for fragment finding - analyzing parkin, a difficult CNS target.
Regnström K, Yan J, Nguyen L, Callaway K, Yang Y, Diep L, Xing W, Adhikari A, Beroza P, Hom RK, Riley B, Rudolph D, Jobling MF, Baker J, Johnston J, Konradi A, Bova MP, Artis DR. Regnström K, et al. Among authors: callaway k. PLoS One. 2013 Jul 5;8(7):e66879. doi: 10.1371/journal.pone.0066879. Print 2013. PLoS One. 2013. PMID: 23861750 Free PMC article.
Proximity-induced catalysis by the protein kinase ERK2.
Rainey MA, Callaway K, Barnes R, Wilson B, Dalby KN. Rainey MA, et al. Among authors: callaway k. J Am Chem Soc. 2005 Aug 3;127(30):10494-5. doi: 10.1021/ja052915p. J Am Chem Soc. 2005. PMID: 16045329 Free PMC article.
33 results