Mandelkow EM - Search Results

1

Identification of Small Molecule Inhibitors of Tau Aggregation by Targeting Monomeric Tau As a Potential Therapeutic Approach for Tauopathies.

Pickhardt M, Neumann T, Schwizer D, Callaway K, Vendruscolo M, Schenk D, St George-Hyslop P, Mandelkow EM, Dobson CM, McConlogue L, Mandelkow E, Tóth G. Pickhardt M, et al. Among authors: mandelkow em, mandelkow e. Curr Alzheimer Res. 2015;12(9):814-28. doi: 10.2174/156720501209151019104951. Curr Alzheimer Res. 2015. PMID: 26510979 Free PMC article.

2

Oxidation of cysteine-322 in the repeat domain of microtubule-associated protein tau controls the in vitro assembly of paired helical filaments.

Schweers O, Mandelkow EM, Biernat J, Mandelkow E. Schweers O, et al. Among authors: mandelkow em, mandelkow e. Proc Natl Acad Sci U S A. 1995 Aug 29;92(18):8463-7. doi: 10.1073/pnas.92.18.8463. Proc Natl Acad Sci U S A. 1995. PMID: 7667312 Free PMC article.

3

Tau protein and Alzheimer's disease.

Mandelkow EM, Mandelkow E. Mandelkow EM, et al. Among authors: mandelkow e. Neurobiol Aging. 1994;15 Suppl 2:S85-6. doi: 10.1016/0197-4580(94)90178-3. Neurobiol Aging. 1994. PMID: 7700470 Review.

4

Tau as a marker for Alzheimer's disease.

Mandelkow EM, Mandelkow E. Mandelkow EM, et al. Among authors: mandelkow e. Trends Biochem Sci. 1993 Dec;18(12):480-3. doi: 10.1016/0968-0004(93)90011-b. Trends Biochem Sci. 1993. PMID: 8108862 Review.

5

The 'jaws' model of tau-microtubule interaction examined in CHO cells.

Preuss U, Biernat J, Mandelkow EM, Mandelkow E. Preuss U, et al. Among authors: mandelkow em, mandelkow e. J Cell Sci. 1997 Mar;110 ( Pt 6):789-800. doi: 10.1242/jcs.110.6.789. J Cell Sci. 1997. PMID: 9099953

6

Rapid assembly of Alzheimer-like paired helical filaments from microtubule-associated protein tau monitored by fluorescence in solution.

Friedhoff P, Schneider A, Mandelkow EM, Mandelkow E. Friedhoff P, et al. Among authors: mandelkow em, mandelkow e. Biochemistry. 1998 Jul 14;37(28):10223-30. doi: 10.1021/bi980537d. Biochemistry. 1998. PMID: 9665729

7

Tau in Alzheimer's disease.

Mandelkow EM, Mandelkow E. Mandelkow EM, et al. Among authors: mandelkow e. Trends Cell Biol. 1998 Nov;8(11):425-7. doi: 10.1016/s0962-8924(98)01368-3. Trends Cell Biol. 1998. PMID: 9854307 Review.

8

Structure, microtubule interactions, and paired helical filament aggregation by tau mutants of frontotemporal dementias.

Barghorn S, Zheng-Fischhöfer Q, Ackmann M, Biernat J, von Bergen M, Mandelkow EM, Mandelkow E. Barghorn S, et al. Among authors: mandelkow em, mandelkow e. Biochemistry. 2000 Sep 26;39(38):11714-21. doi: 10.1021/bi000850r. Biochemistry. 2000. PMID: 10995239

9

Anthraquinones inhibit tau aggregation and dissolve Alzheimer's paired helical filaments in vitro and in cells.

Pickhardt M, Gazova Z, von Bergen M, Khlistunova I, Wang Y, Hascher A, Mandelkow EM, Biernat J, Mandelkow E. Pickhardt M, et al. Among authors: mandelkow em, mandelkow e. J Biol Chem. 2005 Feb 4;280(5):3628-35. doi: 10.1074/jbc.M410984200. Epub 2004 Nov 2. J Biol Chem. 2005. PMID: 15525637 Free article.

10

Screening for inhibitors of tau polymerization.

Pickhardt M, von Bergen M, Gazova Z, Hascher A, Biernat J, Mandelkow EM, Mandelkow E. Pickhardt M, et al. Among authors: mandelkow em, mandelkow e. Curr Alzheimer Res. 2005 Apr;2(2):219-26. doi: 10.2174/1567205053585891. Curr Alzheimer Res. 2005. PMID: 15974921

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