Vendruscolo M - Search Results

1

Identification of Small Molecule Inhibitors of Tau Aggregation by Targeting Monomeric Tau As a Potential Therapeutic Approach for Tauopathies.

Pickhardt M, Neumann T, Schwizer D, Callaway K, Vendruscolo M, Schenk D, St George-Hyslop P, Mandelkow EM, Dobson CM, McConlogue L, Mandelkow E, Tóth G. Pickhardt M, et al. Among authors: vendruscolo m. Curr Alzheimer Res. 2015;12(9):814-28. doi: 10.2174/156720501209151019104951. Curr Alzheimer Res. 2015. PMID: 26510979 Free PMC article.

2

Three key residues form a critical contact network in a protein folding transition state.

Vendruscolo M, Paci E, Dobson CM, Karplus M. Vendruscolo M, et al. Nature. 2001 Feb 1;409(6820):641-5. doi: 10.1038/35054591. Nature. 2001. PMID: 11214326

3

Determination of a transition state at atomic resolution from protein engineering data.

Paci E, Vendruscolo M, Dobson CM, Karplus M. Paci E, et al. Among authors: vendruscolo m. J Mol Biol. 2002 Nov 15;324(1):151-63. doi: 10.1016/s0022-2836(02)00944-0. J Mol Biol. 2002. PMID: 12421565

4

Protein folding and misfolding: a paradigm of self-assembly and regulation in complex biological systems.

Vendruscolo M, Zurdo J, MacPhee CE, Dobson CM. Vendruscolo M, et al. Philos Trans A Math Phys Eng Sci. 2003 Jun 15;361(1807):1205-22. doi: 10.1098/rsta.2003.1194. Philos Trans A Math Phys Eng Sci. 2003. PMID: 12816607

5

Calculation of mutational free energy changes in transition states for protein folding.

Lindorff-Larsen K, Paci E, Serrano L, Dobson CM, Vendruscolo M. Lindorff-Larsen K, et al. Among authors: vendruscolo m. Biophys J. 2003 Aug;85(2):1207-14. doi: 10.1016/S0006-3495(03)74556-1. Biophys J. 2003. PMID: 12885664 Free PMC article.

6

Structures and relative free energies of partially folded states of proteins.

Vendruscolo M, Paci E, Karplus M, Dobson CM. Vendruscolo M, et al. Proc Natl Acad Sci U S A. 2003 Dec 9;100(25):14817-21. doi: 10.1073/pnas.2036516100. Epub 2003 Dec 1. Proc Natl Acad Sci U S A. 2003. PMID: 14657374 Free PMC article.

7

Rare fluctuations of native proteins sampled by equilibrium hydrogen exchange.

Vendruscolo M, Paci E, Dobson CM, Karplus M. Vendruscolo M, et al. J Am Chem Soc. 2003 Dec 24;125(51):15686-7. doi: 10.1021/ja036523z. J Am Chem Soc. 2003. PMID: 14677926

8

Determination of an ensemble of structures representing the denatured state of the bovine acyl-coenzyme a binding protein.

Lindorff-Larsen K, Kristjansdottir S, Teilum K, Fieber W, Dobson CM, Poulsen FM, Vendruscolo M. Lindorff-Larsen K, et al. Among authors: vendruscolo m. J Am Chem Soc. 2004 Mar 17;126(10):3291-9. doi: 10.1021/ja039250g. J Am Chem Soc. 2004. PMID: 15012160

9

Transition states for protein folding have native topologies despite high structural variability.

Lindorff-Larsen K, Vendruscolo M, Paci E, Dobson CM. Lindorff-Larsen K, et al. Among authors: vendruscolo m. Nat Struct Mol Biol. 2004 May;11(5):443-9. doi: 10.1038/nsmb765. Epub 2004 Apr 18. Nat Struct Mol Biol. 2004. PMID: 15098020

10

Prediction of the absolute aggregation rates of amyloidogenic polypeptide chains.

DuBay KF, Pawar AP, Chiti F, Zurdo J, Dobson CM, Vendruscolo M. DuBay KF, et al. Among authors: vendruscolo m. J Mol Biol. 2004 Aug 27;341(5):1317-26. doi: 10.1016/j.jmb.2004.06.043. J Mol Biol. 2004. PMID: 15302561

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