Samelson LE - Search Results

1

Cish actively silences TCR signaling in CD8+ T cells to maintain tumor tolerance.

Palmer DC, Guittard GC, Franco Z, Crompton JG, Eil RL, Patel SJ, Ji Y, Van Panhuys N, Klebanoff CA, Sukumar M, Clever D, Chichura A, Roychoudhuri R, Varma R, Wang E, Gattinoni L, Marincola FM, Balagopalan L, Samelson LE, Restifo NP. Palmer DC, et al. Among authors: samelson le. J Exp Med. 2015 Nov 16;212(12):2095-113. doi: 10.1084/jem.20150304. Epub 2015 Nov 2. J Exp Med. 2015. PMID: 26527801 Free PMC article.

2

Regulation of T cell receptor expression in immature CD4+CD8+ thymocytes by p56lck tyrosine kinase: basis for differential signaling by CD4 and CD8 in immature thymocytes expressing both coreceptor molecules.

Wiest DL, Yuan L, Jefferson J, Benveniste P, Tsokos M, Klausner RD, Glimcher LH, Samelson LE, Singer A. Wiest DL, et al. Among authors: samelson le. J Exp Med. 1993 Nov 1;178(5):1701-12. doi: 10.1084/jem.178.5.1701. J Exp Med. 1993. PMID: 8228817 Free PMC article.

3

Association of the adaptor molecule LAT with CD4 and CD8 coreceptors identifies a new coreceptor function in T cell receptor signal transduction.

Bosselut R, Zhang W, Ashe JM, Kopacz JL, Samelson LE, Singer A. Bosselut R, et al. Among authors: samelson le. J Exp Med. 1999 Nov 15;190(10):1517-26. doi: 10.1084/jem.190.10.1517. J Exp Med. 1999. PMID: 10562325 Free PMC article.

4

Knock-in mutation of the distal four tyrosines of linker for activation of T cells blocks murine T cell development.

Sommers CL, Menon RK, Grinberg A, Zhang W, Samelson LE, Love PE. Sommers CL, et al. Among authors: samelson le. J Exp Med. 2001 Jul 16;194(2):135-42. doi: 10.1084/jem.194.2.135. J Exp Med. 2001. PMID: 11457888 Free PMC article.

5

The four distal tyrosines are required for LAT-dependent signaling in FcepsilonRI-mediated mast cell activation.

Saitoh S, Odom S, Gomez G, Sommers CL, Young HA, Rivera J, Samelson LE. Saitoh S, et al. Among authors: samelson le. J Exp Med. 2003 Sep 1;198(5):831-43. doi: 10.1084/jem.20030574. J Exp Med. 2003. PMID: 12953098 Free PMC article.

6

Inactivation of c-Cbl reverses neonatal lethality and T cell developmental arrest of SLP-76-deficient mice.

Chiang YJ, Sommers CL, Jordan MS, Gu H, Samelson LE, Koretzky GA, Hodes RJ. Chiang YJ, et al. Among authors: samelson le. J Exp Med. 2004 Jul 5;200(1):25-34. doi: 10.1084/jem.20040262. J Exp Med. 2004. PMID: 15238603 Free PMC article.

7

Mutation of the phospholipase C-gamma1-binding site of LAT affects both positive and negative thymocyte selection.

Sommers CL, Lee J, Steiner KL, Gurson JM, Depersis CL, El-Khoury D, Fuller CL, Shores EW, Love PE, Samelson LE. Sommers CL, et al. Among authors: samelson le. J Exp Med. 2005 Apr 4;201(7):1125-34. doi: 10.1084/jem.20041869. Epub 2005 Mar 28. J Exp Med. 2005. PMID: 15795236 Free PMC article.

8

T-cell antigen receptor-induced signaling complexes: internalization via a cholesterol-dependent endocytic pathway.

Barr VA, Balagopalan L, Barda-Saad M, Polishchuk R, Boukari H, Bunnell SC, Bernot KM, Toda Y, Nossal R, Samelson LE. Barr VA, et al. Among authors: samelson le. Traffic. 2006 Sep;7(9):1143-62. doi: 10.1111/j.1600-0854.2006.00464.x. Traffic. 2006. PMID: 16919152 Free article.

9

c-Cbl-mediated regulation of LAT-nucleated signaling complexes.

Balagopalan L, Barr VA, Sommers CL, Barda-Saad M, Goyal A, Isakowitz MS, Samelson LE. Balagopalan L, et al. Among authors: samelson le. Mol Cell Biol. 2007 Dec;27(24):8622-36. doi: 10.1128/MCB.00467-07. Epub 2007 Oct 15. Mol Cell Biol. 2007. PMID: 17938199 Free PMC article.

10

Dynamic movement of the calcium sensor STIM1 and the calcium channel Orai1 in activated T-cells: puncta and distal caps.

Barr VA, Bernot KM, Srikanth S, Gwack Y, Balagopalan L, Regan CK, Helman DJ, Sommers CL, Oh-Hora M, Rao A, Samelson LE. Barr VA, et al. Among authors: samelson le. Mol Biol Cell. 2008 Jul;19(7):2802-17. doi: 10.1091/mbc.e08-02-0146. Epub 2008 Apr 30. Mol Biol Cell. 2008. PMID: 18448669 Free PMC article.

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