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IRE1α is an endogenous substrate of endoplasmic-reticulum-associated degradation.
Sun S, Shi G, Sha H, Ji Y, Han X, Shu X, Ma H, Inoue T, Gao B, Kim H, Bu P, Guber RD, Shen X, Lee AH, Iwawaki T, Paton AW, Paton JC, Fang D, Tsai B, Yates JR 3rd, Wu H, Kersten S, Long Q, Duhamel GE, Simpson KW, Qi L. Sun S, et al. Among authors: guber rd. Nat Cell Biol. 2015 Dec;17(12):1546-55. doi: 10.1038/ncb3266. Epub 2015 Nov 9. Nat Cell Biol. 2015. PMID: 26551274 Free PMC article.
The ER-associated degradation adaptor protein Sel1L regulates LPL secretion and lipid metabolism.
Sha H, Sun S, Francisco AB, Ehrhardt N, Xue Z, Liu L, Lawrence P, Mattijssen F, Guber RD, Panhwar MS, Brenna JT, Shi H, Xue B, Kersten S, Bensadoun A, Péterfy M, Long Q, Qi L. Sha H, et al. Among authors: guber rd. Cell Metab. 2014 Sep 2;20(3):458-70. doi: 10.1016/j.cmet.2014.06.015. Epub 2014 Jul 24. Cell Metab. 2014. PMID: 25066055 Free PMC article.
Impending Backlog of Cleft Palate Patients Due to COVID-19.
Wood JJ, Gu G, Guber RD, Rothkopf DM. Wood JJ, et al. Among authors: guber rd. Ann Glob Health. 2022 Jan 20;88(1):9. doi: 10.5334/aogh.3534. eCollection 2022. Ann Glob Health. 2022. PMID: 35087709 Free PMC article.
Safety, tolerability, and preliminary efficacy of an IGF-1 mimetic in patients with spinal and bulbar muscular atrophy: a randomised, placebo-controlled trial.
Grunseich C, Miller R, Swan T, Glass DJ, El Mouelhi M, Fornaro M, Petricoul O, Vostiar I, Roubenoff R, Meriggioli MN, Kokkinis A, Guber RD, Budron MS, Vissing J, Soraru G, Mozaffar T, Ludolph A, Kissel JT, Fischbeck KH; BVS857 study group. Grunseich C, et al. Among authors: guber rd. Lancet Neurol. 2018 Dec;17(12):1043-1052. doi: 10.1016/S1474-4422(18)30320-X. Epub 2018 Oct 15. Lancet Neurol. 2018. PMID: 30337273 Free PMC article. Clinical Trial.
Senataxin Mutation Reveals How R-Loops Promote Transcription by Blocking DNA Methylation at Gene Promoters.
Grunseich C, Wang IX, Watts JA, Burdick JT, Guber RD, Zhu Z, Bruzel A, Lanman T, Chen K, Schindler AB, Edwards N, Ray-Chaudhury A, Yao J, Lehky T, Piszczek G, Crain B, Fischbeck KH, Cheung VG. Grunseich C, et al. Among authors: guber rd. Mol Cell. 2018 Feb 1;69(3):426-437.e7. doi: 10.1016/j.molcel.2017.12.030. Epub 2018 Jan 27. Mol Cell. 2018. PMID: 29395064 Free PMC article.
Nonalcoholic fatty liver disease in spinal and bulbar muscular atrophy.
Guber RD, Takyar V, Kokkinis A, Fox DA, Alao H, Kats I, Bakar D, Remaley AT, Hewitt SM, Kleiner DE, Liu CY, Hadigan C, Fischbeck KH, Rotman Y, Grunseich C. Guber RD, et al. Neurology. 2017 Dec 12;89(24):2481-2490. doi: 10.1212/WNL.0000000000004748. Epub 2017 Nov 15. Neurology. 2017. PMID: 29142082 Free PMC article.