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IRE1α is an endogenous substrate of endoplasmic-reticulum-associated degradation.
Sun S, Shi G, Sha H, Ji Y, Han X, Shu X, Ma H, Inoue T, Gao B, Kim H, Bu P, Guber RD, Shen X, Lee AH, Iwawaki T, Paton AW, Paton JC, Fang D, Tsai B, Yates JR 3rd, Wu H, Kersten S, Long Q, Duhamel GE, Simpson KW, Qi L. Sun S, et al. Among authors: lee ah. Nat Cell Biol. 2015 Dec;17(12):1546-55. doi: 10.1038/ncb3266. Epub 2015 Nov 9. Nat Cell Biol. 2015. PMID: 26551274 Free PMC article.
IRE1α activation protects mice against acetaminophen-induced hepatotoxicity.
Hur KY, So JS, Ruda V, Frank-Kamenetsky M, Fitzgerald K, Koteliansky V, Iwawaki T, Glimcher LH, Lee AH. Hur KY, et al. Among authors: lee ah. J Exp Med. 2012 Feb 13;209(2):307-18. doi: 10.1084/jem.20111298. Epub 2012 Jan 30. J Exp Med. 2012. PMID: 22291093 Free PMC article.
ER Stress Sensor XBP1 Controls Anti-tumor Immunity by Disrupting Dendritic Cell Homeostasis.
Cubillos-Ruiz JR, Silberman PC, Rutkowski MR, Chopra S, Perales-Puchalt A, Song M, Zhang S, Bettigole SE, Gupta D, Holcomb K, Ellenson LH, Caputo T, Lee AH, Conejo-Garcia JR, Glimcher LH. Cubillos-Ruiz JR, et al. Among authors: lee ah. Cell. 2015 Jun 18;161(7):1527-38. doi: 10.1016/j.cell.2015.05.025. Epub 2015 Jun 11. Cell. 2015. PMID: 26073941 Free PMC article.
1,219 results