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SGLT2 mediates glucose reabsorption in the early proximal tubule.
Vallon V, Platt KA, Cunard R, Schroth J, Whaley J, Thomson SC, Koepsell H, Rieg T. Vallon V, et al. Among authors: rieg t. J Am Soc Nephrol. 2011 Jan;22(1):104-12. doi: 10.1681/ASN.2010030246. Epub 2010 Jul 8. J Am Soc Nephrol. 2011. PMID: 20616166 Free PMC article.
Na(+)-D-glucose cotransporter SGLT1 is pivotal for intestinal glucose absorption and glucose-dependent incretin secretion.
Gorboulev V, Schürmann A, Vallon V, Kipp H, Jaschke A, Klessen D, Friedrich A, Scherneck S, Rieg T, Cunard R, Veyhl-Wichmann M, Srinivasan A, Balen D, Breljak D, Rexhepaj R, Parker HE, Gribble FM, Reimann F, Lang F, Wiese S, Sabolic I, Sendtner M, Koepsell H. Gorboulev V, et al. Among authors: rieg t. Diabetes. 2012 Jan;61(1):187-96. doi: 10.2337/db11-1029. Epub 2011 Nov 28. Diabetes. 2012. PMID: 22124465 Free PMC article.
SGLT2 inhibitor empagliflozin reduces renal growth and albuminuria in proportion to hyperglycemia and prevents glomerular hyperfiltration in diabetic Akita mice.
Vallon V, Gerasimova M, Rose MA, Masuda T, Satriano J, Mayoux E, Koepsell H, Thomson SC, Rieg T. Vallon V, et al. Among authors: rieg t. Am J Physiol Renal Physiol. 2014 Jan;306(2):F194-204. doi: 10.1152/ajprenal.00520.2013. Epub 2013 Nov 13. Am J Physiol Renal Physiol. 2014. PMID: 24226524 Free PMC article.
Renal phosphate wasting in the absence of adenylyl cyclase 6.
Fenton RA, Murray F, Dominguez Rieg JA, Tang T, Levi M, Rieg T. Fenton RA, et al. Among authors: rieg t. J Am Soc Nephrol. 2014 Dec;25(12):2822-34. doi: 10.1681/ASN.2013101102. Epub 2014 May 22. J Am Soc Nephrol. 2014. PMID: 24854272 Free PMC article.
Caffeine-induced diuresis and natriuresis is independent of renal tubular NHE3.
Fenton RA, Poulsen SB, de la Mora Chavez S, Soleimani M, Busslinger M, Dominguez Rieg JA, Rieg T. Fenton RA, et al. Among authors: rieg t. Am J Physiol Renal Physiol. 2015 Jun 15;308(12):F1409-20. doi: 10.1152/ajprenal.00129.2015. Epub 2015 Apr 29. Am J Physiol Renal Physiol. 2015. PMID: 25925253 Free PMC article.
117 results