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Page 1
Polymorphisms of large effect explain the majority of the host genetic contribution to variation of HIV-1 virus load.
McLaren PJ, Coulonges C, Bartha I, Lenz TL, Deutsch AJ, Bashirova A, Buchbinder S, Carrington MN, Cossarizza A, Dalmau J, De Luca A, Goedert JJ, Gurdasani D, Haas DW, Herbeck JT, Johnson EO, Kirk GD, Lambotte O, Luo M, Mallal S, van Manen D, Martinez-Picado J, Meyer L, Miro JM, Mullins JI, Obel N, Poli G, Sandhu MS, Schuitemaker H, Shea PR, Theodorou I, Walker BD, Weintrob AC, Winkler CA, Wolinsky SM, Raychaudhuri S, Goldstein DB, Telenti A, de Bakker PI, Zagury JF, Fellay J. McLaren PJ, et al. Among authors: mallal s. Proc Natl Acad Sci U S A. 2015 Nov 24;112(47):14658-63. doi: 10.1073/pnas.1514867112. Epub 2015 Nov 9. Proc Natl Acad Sci U S A. 2015. PMID: 26553974 Free PMC article.
Effects of CCR5-Delta32, CCR2-64I, and SDF-1 3'A alleles on HIV-1 disease progression: An international meta-analysis of individual-patient data.
Ioannidis JP, Rosenberg PS, Goedert JJ, Ashton LJ, Benfield TL, Buchbinder SP, Coutinho RA, Eugen-Olsen J, Gallart T, Katzenstein TL, Kostrikis LG, Kuipers H, Louie LG, Mallal SA, Margolick JB, Martinez OP, Meyer L, Michael NL, Operskalski E, Pantaleo G, Rizzardi GP, Schuitemaker H, Sheppard HW, Stewart GJ, Theodorou ID, Ullum H, Vicenzi E, Vlahov D, Wilkinson D, Workman C, Zagury JF, O'Brien TR; International Meta-Analysis of HIV Host Genetics. Ioannidis JP, et al. Among authors: mallal sa. Ann Intern Med. 2001 Nov 6;135(9):782-95. doi: 10.7326/0003-4819-135-9-200111060-00008. Ann Intern Med. 2001. PMID: 11694103
HLA and HIV: modeling adaptation to moving targets.
Telenti A, Beckmann JS, Mallal S. Telenti A, et al. Among authors: mallal s. Pharmacogenomics J. 2003;3(5):254-6. doi: 10.1038/sj.tpj.6500200. Pharmacogenomics J. 2003. PMID: 14583794 No abstract available.
Selection, transmission, and reversion of an antigen-processing cytotoxic T-lymphocyte escape mutation in human immunodeficiency virus type 1 infection.
Allen TM, Altfeld M, Yu XG, O'Sullivan KM, Lichterfeld M, Le Gall S, John M, Mothe BR, Lee PK, Kalife ET, Cohen DE, Freedberg KA, Strick DA, Johnston MN, Sette A, Rosenberg ES, Mallal SA, Goulder PJ, Brander C, Walker BD. Allen TM, et al. Among authors: mallal sa. J Virol. 2004 Jul;78(13):7069-78. doi: 10.1128/JVI.78.13.7069-7078.2004. J Virol. 2004. PMID: 15194783 Free PMC article.
Dominant influence of HLA-B in mediating the potential co-evolution of HIV and HLA.
Kiepiela P, Leslie AJ, Honeyborne I, Ramduth D, Thobakgale C, Chetty S, Rathnavalu P, Moore C, Pfafferott KJ, Hilton L, Zimbwa P, Moore S, Allen T, Brander C, Addo MM, Altfeld M, James I, Mallal S, Bunce M, Barber LD, Szinger J, Day C, Klenerman P, Mullins J, Korber B, Coovadia HM, Walker BD, Goulder PJ. Kiepiela P, et al. Among authors: mallal s. Nature. 2004 Dec 9;432(7018):769-75. doi: 10.1038/nature03113. Nature. 2004. PMID: 15592417
De novo generation of escape variant-specific CD8+ T-cell responses following cytotoxic T-lymphocyte escape in chronic human immunodeficiency virus type 1 infection.
Allen TM, Yu XG, Kalife ET, Reyor LL, Lichterfeld M, John M, Cheng M, Allgaier RL, Mui S, Frahm N, Alter G, Brown NV, Johnston MN, Rosenberg ES, Mallal SA, Brander C, Walker BD, Altfeld M. Allen TM, et al. Among authors: mallal sa. J Virol. 2005 Oct;79(20):12952-60. doi: 10.1128/JVI.79.20.12952-12960.2005. J Virol. 2005. PMID: 16188997 Free PMC article.
Selective escape from CD8+ T-cell responses represents a major driving force of human immunodeficiency virus type 1 (HIV-1) sequence diversity and reveals constraints on HIV-1 evolution.
Allen TM, Altfeld M, Geer SC, Kalife ET, Moore C, O'sullivan KM, Desouza I, Feeney ME, Eldridge RL, Maier EL, Kaufmann DE, Lahaie MP, Reyor L, Tanzi G, Johnston MN, Brander C, Draenert R, Rockstroh JK, Jessen H, Rosenberg ES, Mallal SA, Walker BD. Allen TM, et al. Among authors: mallal sa. J Virol. 2005 Nov;79(21):13239-49. doi: 10.1128/JVI.79.21.13239-13249.2005. J Virol. 2005. PMID: 16227247 Free PMC article.
Control of human immunodeficiency virus replication by cytotoxic T lymphocytes targeting subdominant epitopes.
Frahm N, Kiepiela P, Adams S, Linde CH, Hewitt HS, Sango K, Feeney ME, Addo MM, Lichterfeld M, Lahaie MP, Pae E, Wurcel AG, Roach T, St John MA, Altfeld M, Marincola FM, Moore C, Mallal S, Carrington M, Heckerman D, Allen TM, Mullins JI, Korber BT, Goulder PJ, Walker BD, Brander C. Frahm N, et al. Among authors: mallal s. Nat Immunol. 2006 Feb;7(2):173-8. doi: 10.1038/ni1281. Epub 2005 Dec 20. Nat Immunol. 2006. PMID: 16369537
Impact of HLA-B alleles, epitope binding affinity, functional avidity, and viral coinfection on the immunodominance of virus-specific CTL responses.
Bihl F, Frahm N, Di Giammarino L, Sidney J, John M, Yusim K, Woodberry T, Sango K, Hewitt HS, Henry L, Linde CH, Chisholm JV 3rd, Zaman TM, Pae E, Mallal S, Walker BD, Sette A, Korber BT, Heckerman D, Brander C. Bihl F, et al. Among authors: mallal s. J Immunol. 2006 Apr 1;176(7):4094-101. doi: 10.4049/jimmunol.176.7.4094. J Immunol. 2006. PMID: 16547245
303 results